Protein Alignment E(spl)m5-HLH and hey2

DIOPT Version :10

• Sequence 1: NP_524511.1
• Gene: E(spl)m5-HLH / 43158
• FlyBaseID: FBgn0002631
• Length: 178
• Species: Drosophila melanogaster
• Sequence 2: NP_571697.2
• Gene: hey2 / 58146
• ZFINID: ZDB-GENE-000526-1
• Length: 324
• Species: Danio rerio
• Alignment Length: 196
• Identity: 48/196 - (24%)
• Similarity: 84/196 - (42%)
• Gaps: 38/196 - (19%)

  Fly     4 QSNNSTTFV-----SKTQHYL--KVKKPLLERQRRARMNKCLDTLKTLVA---EFQGDDAILRMD 58
            |||.|  |:     :.|...:  |.::.::|::||.|:|..|..|:.||.   |.||.   .:::
Zfish    29 QSNGS--FIRCGSPTTTSQVMARKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS---AKLE 88

  Fly    59 KAEMLEAA---LVFMRKQVVKQQAPVSPLPMDSFKNGYMNAVSEISRVMACTPAM--SVDVGKTV 118
            |||:|:..   |..::....|.......|.||....|:...::|::|.::....:  |..:...:
Zfish    89 KAEILQMTVDHLKMLQATGGKGYFDAHSLAMDFLSIGFRECLTEVARYLSSVEGLDSSDPLRVRL 153

  Fly   119 MTHL-GVEFQRMLQADQVQTSVT-----------TSTPRPLSPA---SSGYHSDNEDSQSAASPK 168
            ::|| ....||  :|..:.||:.           .:...|:..|   .||..| :|.|....|..
Zfish   154 VSHLSSCASQR--EAAAMTTSIAHHQQALHPHHWAAALHPIPAAFLQQSGLPS-SESSSGRLSEA 215

  Fly   169 P 169
            |
Zfish   216 P 216

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m5-HLH	NP_524511.1	bHLH-O_ESM5_like	20..78	CDD:381486	19/63 (30%)
		ORANGE	87..131	CDD:128787	9/46 (20%)
hey2	NP_571697.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34		4/6 (67%)
		bHLH-O_HEY2	40..121	CDD:381490	22/83 (27%)
		ORANGE	119..165	CDD:128787	10/47 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	294..324
		YRPW motif	314..317