Protein Alignment E(spl)m5-HLH and hey1

DIOPT Version :10

• Sequence 1: NP_524511.1
• Gene: E(spl)m5-HLH / 43158
• FlyBaseID: FBgn0002631
• Length: 178
• Species: Drosophila melanogaster
• Sequence 2: NP_997726.2
• Gene: hey1 / 58008
• ZFINID: ZDB-GENE-000607-70
• Length: 318
• Species: Danio rerio
• Alignment Length: 201
• Identity: 47/201 - (23%)
• Similarity: 83/201 - (41%)
• Gaps: 45/201 - (22%)

  Fly     2 APQSNNSTTFVSKTQHYLKVKKPLLERQRRARMNKCLDTLKTLVA---EFQGDDAILRMDKAEML 63
            :|..:.|.:..|:.| ..|.::.::|::||.|:|..|..|:.||.   |.||.   .:::|||:|
Zfish    33 SPLGSMSPSTTSQVQ-ARKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGS---AKLEKAEIL 93

  Fly    64 EAA---LVFMRKQVVKQQAPVSPLPMDSFKNGYMNAVSEISRVMACTPAM-SVD-VGKTVMTHL- 122
            :..   |..:.....|.......|.||....|:...::|.:|.::....: :.| :...:::||
Zfish    94 QMTVDHLKMLHAAGGKGYFDAHALAMDYRGLGFRECLAETARYLSIIEGLDNTDPLRIRLVSHLN 158

  Fly   123 -----------------GVEF---------QRMLQADQVQTSVTTSTPRPLSPASSGYHSDNEDS 161
                             |..|         ..:||..|.|...      ||:.::|...|.|..|
Zfish   159 SYASQREAHSGLGHLAWGSAFGTPPSHLAHHLLLQQQQQQQGA------PLARSTSSPPSSNSSS 217

  Fly   162 QSAASP 167
            .|::||
Zfish   218 PSSSSP 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m5-HLH	NP_524511.1	bHLH-O_ESM5_like	20..78	CDD:381486	19/63 (30%)
		ORANGE	87..131	CDD:128787	9/72 (13%)
hey1	NP_997726.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..59		6/26 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..265		11/36 (31%)
		YRPW motif	308..311