Protein Alignment E(spl)m5-HLH and Hes6

DIOPT Version :9

• Sequence 1: NP_524511.1
• Gene: E(spl)m5-HLH / 43158
• FlyBaseID: FBgn0002631
• Length: 178
• Species: Drosophila melanogaster
• Sequence 2: NP_062352.1
• Gene: Hes6 / 55927
• MGIID: 1859852
• Length: 224
• Species: Mus musculus
• Alignment Length: 206
• Identity: 55/206 - (26%)
• Similarity: 88/206 - (42%)
• Gaps: 55/206 - (26%)

  Fly    20 KVKKPLLERQRRARMNKCLDTLKTLVAEFQGDDAILRMDKAEMLE-------AALVFMRKQVVKQ 77
            |.:|||:|::||||:|:.|..|:.|:|   |.:...:::.||:||       .||....::..:.
Mouse    27 KARKPLVEKKRRARINESLQELRLLLA---GTEVQAKLENAEVLELTVRRVQGALRGRAREREQL 88

  Fly    78 QAPVSPLPMDSFKNGYMNAVSEISRVMACTPAMSVDVGKTVMTHL--------GVEFQRMLQADQ 134
            ||..|    :.|..||:..:.|:...::...|:...|...::.||        |..||.:| .|.
Mouse    89 QAEAS----ERFAAGYIQCMHEVHTFVSTCQAIDATVSAELLNHLLESMPLREGSSFQDLL-GDS 148

  Fly   135 VQ----TSVTTSTP---RPLSPASS------GYHSDNEDSQSAASPK-PVE-------------- 171
            :.    .|..:|.|   .|.||.||      ...||.|:...|...: |.|
Mouse   149 LAGLPGGSGRSSWPPGGSPESPLSSPPGPGDDLCSDLEEIPEAELNRVPAEGPDLVSTSLGSLTA 213

  Fly   172 ----ETMWRPW 178
                :::||||
Mouse   214 ARRAQSVWRPW 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m5-HLH	NP_524511.1	HLH	20..72	CDD:238036	21/58 (36%)
		ORANGE	87..131	CDD:128787	11/51 (22%)
Hes6	NP_062352.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..31		1/3 (33%)
		bHLH_SF	24..81	CDD:412148	21/56 (38%)
		Hairy_orange	96..134	CDD:400076	8/37 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	146..209		15/62 (24%)
		WRPW motif	221..224		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830824
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.700