Protein Alignment E(spl)m5-HLH and Helt

DIOPT Version :10

• Sequence 1: NP_524511.1
• Gene: E(spl)m5-HLH / 43158
• FlyBaseID: FBgn0002631
• Length: 178
• Species: Drosophila melanogaster
• Sequence 2: XP_008769494.1
• Gene: Helt / 498633
• RGDID: 1564073
• Length: 241
• Species: Rattus norvegicus
• Alignment Length: 173
• Identity: 37/173 - (21%)
• Similarity: 68/173 - (39%)
• Gaps: 23/173 - (13%)

  Fly    21 VKKPLLERQRRARMNKCLDTLKTLVAEFQGDDAILRMDKAEMLEAALVFMRK------QVVKQQA 79
            |...::|::||.|:|:||:.|...|.......:..:::|||:||..:.::|.      ...:::|
  Rat    13 VSHKVIEKRRRDRINRCLNELGKTVPMALAKQSSGKLEKAEILEMTVQYLRALHSADFPRGREKA 77

  Fly    80 PVSPLPMDSFKNGYMNAVSEISRVMACTPAMSVDVGKTVMTHLGVEFQRMLQADQVQTSVTTSTP 144
            .:.....:.|..||...:..:...:.....|.....|.......::.:..|.|:.....:  |.|
  Rat    78 ELLAEFANYFHYGYHECMKNLVHYLTTVERMETKDTKYARILAFLQSKARLGAEPAFPPL--SLP 140

  Fly   145 RP-----LSPASSGY--HSDNEDS--QSAASPKPVEETMWRPW 178
            .|     |.||...:  ||..|.:  ...|:|...      ||
  Rat   141 EPDFSYQLHPAGPEFPGHSPGEATVFPQGATPGSF------PW 177

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m5-HLH	NP_524511.1	bHLH-O_ESM5_like	20..78	CDD:381486	16/62 (26%)
		ORANGE	87..131	CDD:128787	5/43 (12%)
Helt	XP_008769494.1	bHLH-O_HELT	14..69	CDD:381414	15/54 (28%)
		Hairy_orange	86..127	CDD:462193	5/40 (13%)
		DUF1373	129..>213	CDD:462093	14/57 (25%)