DRSC/TRiP Functional Genomics Resources

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Protein Alignment E(spl)m5-HLH and hes1

DIOPT Version :9

Sequence 1:NP_524511.1 Gene:E(spl)m5-HLH / 43158 FlyBaseID:FBgn0002631 Length:178 Species:Drosophila melanogaster
Sequence 2:NP_001011194.1 Gene:hes1 / 496617 XenbaseID:XB-GENE-487995 Length:267 Species:Xenopus tropicalis


Alignment Length:250 Identity:54/250 - (21%)
Similarity:101/250 - (40%) Gaps:74/250 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 PQSNNSTTFVSKT-QHYLKVKKPLLERQRRARMNKCLDTLKTLVAEFQGDDAI--LRMDKAEMLE 64
            |.|.::|....|| ..:.|..||::|::||||:|:.|..||||:.:....|:.  .:::||::||
 Frog    18 PASMSNTPDKPKTASEHRKSSKPIMEKRRRARINESLGQLKTLILDALKKDSSRHSKLEKADILE 82

  Fly    65 AALVFMRK-QVVKQQAPVS--PLPMDSFKNGYMNAVSEISRVMACTPAMSVDVGKTVMTHL---- 122
            ..:..:|. |.|:..|.:|  |..:..::.|:...::|::|.::....::.||...::.||    
 Frog    83 MTVKHLRNLQRVQMTAALSTDPSVLGKYRAGFSECMNEVTRFLSTCEGVNTDVRTRLLGHLANCM 147

  Fly   123 ------GVEFQRMLQAD------------QVQTSVTTSTPRPLS--------------------P 149
                  ....|..:.|.            |:|.:...|:|.|::                    |
 Frog   148 NQINAMNYPTQPQIPAAAAPHPAYGQPLVQLQGAAPQSSPAPIACKMGGPPVEAAKVYGGFQLVP 212

  Fly   150 ASSG--------------------YHSDNEDS------QSAASPKPVEETMWRPW 178
            |..|                    |.:.|..:      ..:..|....:::||||
 Frog   213 APDGQFAFLITNPAFPHNGSVIPVYTNSNVGTALPPSVSPSVMPSVTADSVWRPW 267

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
E(spl)m5-HLHNP_524511.1 HLH 20..72 CDD:238036 19/53 (36%)
ORANGE 87..131 CDD:128787 8/53 (15%)
hes1NP_001011194.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..45 9/26 (35%)
bHLH-O_HES1_4 33..95 CDD:381465 21/61 (34%)
Hairy_orange 110..148 CDD:369405 7/37 (19%)
WRPW motif. /evidence=ECO:0000255 264..267 2/2 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000785
OrthoInspector 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR10985
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
33.010

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