Protein Alignment E(spl)m5-HLH and E(spl)m3-HLH

DIOPT Version :10

• Sequence 1: NP_524511.1
• Gene: E(spl)m5-HLH / 43158
• FlyBaseID: FBgn0002631
• Length: 178
• Species: Drosophila melanogaster
• Sequence 2: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Alignment Length: 227
• Identity: 68/227 - (29%)
• Similarity: 104/227 - (45%)
• Gaps: 67/227 - (29%)

  Fly    12 VSKTQHYLKVKKPLLERQRRARMNKCLDTLKTLVAEF--QGDDAILRMDKAEMLEAALVFMRKQV 74
            :|||..|.||.||||||:||||:|||||.||.|:.|.  |..:.:.|::||::||..:..|||
  Fly     5 MSKTYQYRKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRK-- 67

  Fly    75 VKQQ---------APVSPLP-------MDSFKNGYMNAVSEISRVMACTPAMSVDVGKTVMTHLG 123
            :||:         |.|...|       ::||::||::|..:|::|:..| ..:.::|:.:|..|.
  Fly    68 LKQRGGLSLQGVVAGVGSPPTSTSTAHVESFRSGYVHAADQITQVLLQT-QQTDEIGRKIMKFLS 131

  Fly   124 ---VEFQRML------QADQVQTSVTTSTPRPLSPASSGY------------------------- 154
               :|.|..|      |....|..:..|:.|...|...||
  Fly   132 TRLIELQTQLLQQQQQQQQHQQQQIPQSSGRLAFPLLGGYGPAAAAAAISYSSFLTSKDELIDVT 196

  Fly   155 --------HSDNEDSQSAASPKPVEETMWRPW 178
                    .:.:..||.:.:.:||    ||||
  Fly   197 SVDGNALSETASVSSQESGASEPV----WRPW 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m5-HLH	NP_524511.1	bHLH-O_ESM5_like	20..78	CDD:381486	31/59 (53%)
		ORANGE	87..131	CDD:128787	14/52 (27%)
E(spl)m3-HLH	NP_524509.2	bHLH-O_ESMB_like	5..71	CDD:381584	35/67 (52%)
		ORANGE	96..136	CDD:128787	11/40 (28%)