Protein Alignment E(spl)m5-HLH and hes4

DIOPT Version :9

• Sequence 1: NP_524511.1
• Gene: E(spl)m5-HLH / 43158
• FlyBaseID: FBgn0002631
• Length: 178
• Species: Drosophila melanogaster
• Sequence 2: NP_988870.1
• Gene: hes4 / 394465
• XenbaseID: XB-GENE-487830
• Length: 281
• Species: Xenopus tropicalis
• Alignment Length: 265
• Identity: 56/265 - (21%)
• Similarity: 105/265 - (39%)
• Gaps: 88/265 - (33%)

  Fly     2 APQSNNSTTFVSKT-QHYLKVKKPLLERQRRARMNKCLDTLKTLVAEFQGDDAI--LRMDKAEML 63
            ||.|:..|....|: ..:.|..||::|::||||:|:.|..||||:.:....|:.  .:::||::|
 Frog    17 APASSAQTPDKPKSASEHRKSSKPIMEKRRRARINESLGQLKTLILDALKKDSSRHSKLEKADIL 81

  Fly    64 EAALVFMRK-QVVKQQAPVS--PLPMDSFKNGYMNAVSEISRVMACTPAMSVDVGKTVMTHL--- 122
            |..:..:|. |.|:..|.::  |..:..::.|:...::|::|.::....::.:|...::.||
 Frog    82 EMTVKHLRNLQRVQMTAALTADPSVLGKYRAGFNECMNEVTRFLSTCEGVNTEVRTRLLGHLSSC 146

  Fly   123 -----GVEFQRMLQADQ-VQTSVTTSTPRP-----------------------LSPASSG----- 153
                 .:.:|:...:.| :...:.:|||.|                       |.||:.|
 Frog   147 LGQIVAMNYQQPPSSQQPLHVQLPSSTPAPVPMPCKVNPAEAISPKVFQGGFQLVPATDGQFAFL 211

  Fly   154 ----------------YHSDNEDSQSA-ASPKPVE----------------------------ET 173
                            |.:.|..|... .|..||:                            |:
 Frog   212 IPNPAYTTSPGPVIPLYANTNVTSPGGPQSQSPVQGLTTFGHKMPHMAQAVSPLGGSTGADSAES 276

  Fly   174 MWRPW 178
            :||||
 Frog   277 VWRPW 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m5-HLH	NP_524511.1	HLH	20..72	CDD:238036	19/53 (36%)
		ORANGE	87..131	CDD:128787	7/51 (14%)
hes4	NP_988870.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..44		8/26 (31%)
		bHLH-O_HES1_4	33..95	CDD:381465	21/61 (34%)
		Hairy_orange	110..147	CDD:369405	6/36 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	262..281		3/18 (17%)
		WRPW motif. /evidence=ECO:0000255	278..281		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000785
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010