DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment E(spl)m5-HLH and Sidpn

DIOPT Version :9

Sequence 1:	NP_524511.1	Gene:	E(spl)m5-HLH / 43158	FlyBaseID:	FBgn0002631	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_523599.1	Gene:	Sidpn / 35168	FlyBaseID:	FBgn0032741	Length:	507	Species:	Drosophila melanogaster

Alignment Length:	185	Identity:	45/185 - (24%)
Similarity:	83/185 - (44%)	Gaps:	28/185 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 NSTTFVSKTQHYLK-VKKPLLERQRRARMNKCLDTLKTLVAEF---------QGDDAILRMDKAE 61
            :||..|:.:|...| ..|||:|::||||:|:.|..||.|:.|.         :|.....:::||:
  Fly    38 SSTQNVTSSQDISKRTNKPLMEKRRRARINQSLAILKALILESTKTQNAKNGEGQAKHTKLEKAD 102

  Fly    62 MLEAAL-VFMRKQVVKQQAPVSPLPMDSFKNGYMNAVSEISRVMACTPAMSVDVGKTVMTHLGVE 125
            :||..: .|.|.:.:....      ::.::.||.:...|::|.:| ||..........:...|.:
  Fly   103 ILELTVRHFQRHRNLDDPT------VNKYRAGYTDCAREVARYLA-TPEPPPMGTMPTLAEPGSK 160

  Fly   126 FQRMLQADQ------VQTSVTTSTPRPLSPASSGYHSDNEDSQSAASPKPVEETM 174
            .:.:...||      |:....::.....||:||.....|...:|    :|.|.::
  Fly   161 ARLLRHLDQCIAEIDVEICPHSTAAFAESPSSSSCFDLNHGKKS----QPEEHSL 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m5-HLH	NP_524511.1	HLH	20..72	CDD:238036	21/62 (34%)
E(spl)m5-HLH	NP_524511.1	ORANGE	87..131	CDD:128787	8/43 (19%)
Sidpn	NP_523599.1	HLH	48..117	CDD:238036	22/68 (32%)
Sidpn	NP_523599.1	Hairy_orange	125..172	CDD:284859	10/47 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438348
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840