Protein Alignment E(spl)m5-HLH and her4.5

DIOPT Version :10

• Sequence 1: NP_524511.1
• Gene: E(spl)m5-HLH / 43158
• FlyBaseID: FBgn0002631
• Length: 178
• Species: Drosophila melanogaster
• Sequence 2: NP_571165.3
• Gene: her4.5 / 30301
• ZFINID: ZDB-GENE-081031-106
• Length: 152
• Species: Danio rerio
• Alignment Length: 184
• Identity: 54/184 - (29%)
• Similarity: 79/184 - (42%)
• Gaps: 38/184 - (20%)

  Fly     1 MAPQSNNSTTFVSKTQHYL--KVKKPLLERQRRARMNKCLDTLKTLVA-EFQGDDAILRMDKAEM 62
            |||....|   :|..:..|  |::||::|:.||.|:|..::.||||:| ||.......|.:||::
Zfish     1 MAPTITGS---ISSRETLLTNKLRKPMVEKIRRERINSSIEKLKTLLAQEFVKQQPDSRQEKADI 62

  Fly    63 LEAALVFMRKQVVKQQAPVSPLPMDSFKNGYMNAVSEISRVMACTPAMSVDVGKTVMTHLGVEFQ 127
            ||..|.|:|:......|.      |........|||.:|:....|.:      .|.:..|.:..|
Zfish    63 LEMTLDFLRRSQKSSAAG------DGRSRCVQEAVSFLSQCPVQTQS------HTRLMKLFLHMQ 115

  Fly   128 RMLQADQ---VQTSVTTSTPRPLSPASSGYHSDNEDSQSAASPKPVEETMWRPW 178
              ..|||   |....||.|           |:::    ||....|....:||||
Zfish   116 --TPADQHTRVDNPQTTET-----------HANS----SAKQHTPAHSHIWRPW 152

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m5-HLH	NP_524511.1	bHLH-O_ESM5_like	20..78	CDD:381486	23/58 (40%)
		ORANGE	87..131	CDD:128787	9/43 (21%)
her4.5	NP_571165.3	bHLH-O_HES5	19..77	CDD:381467	23/57 (40%)
		ORANGE	77..123	CDD:128787	13/59 (22%)