Protein Alignment E(spl)m5-HLH and Hes7

DIOPT Version :10

• Sequence 1: NP_524511.1
• Gene: E(spl)m5-HLH / 43158
• FlyBaseID: FBgn0002631
• Length: 178
• Species: Drosophila melanogaster
• Sequence 2: XP_038941367.1
• Gene: Hes7 / 287423
• RGDID: 1305914
• Length: 358
• Species: Rattus norvegicus
• Alignment Length: 212
• Identity: 52/212 - (24%)
• Similarity: 90/212 - (42%)
• Gaps: 49/212 - (23%)

  Fly     3 PQSNNSTT--FVSKTQ-----------HYLKVKKPLLERQRRARMNKCLDTLKTLVAEFQGDDAI 54
            ||:.:.|.  ||.|:.           .:.::.|||:|::||.|:|:.|:.|:.|:.|...|..:
  Rat    13 PQAPSLTCRHFVLKSPGVDISFCRGSCFWFEMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNL 77

  Fly    55 L--RMDKAEMLEAALVFMRKQV----------VKQQAPVSPLPMDSFKNGYMNAVSEISRVMACT 107
            .  :::|||:||.|:.::|::.          |.|:.........:.:.| ..|.||:.|.:...
  Rat    78 RNPKLEKAEILEFAVGYLRERSRVEPPGTARGVGQRREAGGWGARNARAG-EGAGSEVDRGVGER 141

  Fly   108 PAMSVDVGKTVMTHLGVEFQR------------MLQADQVQTSVTTS--------TPRP--LSPA 150
            ||:..|........|.:...|            .|.|.....|:..:        .|||  |.||
  Rat   142 PAVLPDEVNNTRACLSLCLPRCPPLHVHPASCLCLCARLTSVSLRPAPSLNPVGPLPRPPVLPPA 206

  Fly   151 SSGY-HSDNEDSQSAAS 166
            :.|. .|..:|:::.||
  Rat   207 APGVPRSPGQDAEALAS 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m5-HLH	NP_524511.1	bHLH-O_ESM5_like	20..78	CDD:381486	21/69 (30%)
		ORANGE	87..131	CDD:128787	10/55 (18%)
Hes7	XP_038941367.1	bHLH-O_HES7	44..102	CDD:381468	20/57 (35%)
		PRK14954	<229..>322	CDD:184918