Protein Alignment E(spl)m5-HLH and Helt

DIOPT Version :10

• Sequence 1: NP_524511.1
• Gene: E(spl)m5-HLH / 43158
• FlyBaseID: FBgn0002631
• Length: 178
• Species: Drosophila melanogaster
• Sequence 2: XP_006509452.1
• Gene: Helt / 234219
• MGIID: 3040955
• Length: 241
• Species: Mus musculus
• Alignment Length: 177
• Identity: 39/177 - (22%)
• Similarity: 68/177 - (38%)
• Gaps: 31/177 - (17%)

  Fly    21 VKKPLLERQRRARMNKCLDTLKTLVAEFQGDDAILRMDKAEMLEAALVFMRK------QVVKQQA 79
            |...::|::||.|:|:||:.|...|.......:..:::|||:||..:.::|.      ...:::|
Mouse    13 VSHKVIEKRRRDRINRCLNELGKTVPMALAKQSSGKLEKAEILEMTVQYLRALHSADFPRGREKA 77

  Fly    80 PVSPLPMDSFKNGYMNAVSEISRVMACTPAMSVDVGKTVMTHLGVEFQRMLQADQVQTSVTTSTP 144
            .:.....:.|..||...:..:...:.....|.....|.......::.:..|.|:  .|....|.|
Mouse    78 ELLAEFANYFHYGYHECMKNLVHYLTTVERMETKDTKYARILAFLQSKARLGAE--PTFPPLSLP 140

  Fly   145 RPLSPASSGYHSDNEDSQSAASPK-----PVEETMWR--------PW 178
            .|          |......||||:     |.|.||:.        ||
Mouse   141 EP----------DFSYQLHAASPEFPGHSPGEATMFPQGATPGSFPW 177

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m5-HLH	NP_524511.1	bHLH-O_ESM5_like	20..78	CDD:381486	16/62 (26%)
		ORANGE	87..131	CDD:128787	5/43 (12%)
Helt	XP_006509452.1	bHLH-O_HELT	14..69	CDD:381414	15/54 (28%)
		Hairy_orange	86..127	CDD:462193	5/40 (13%)
		PLN02983	<147..>213	CDD:215533	10/31 (32%)