Protein Alignment E(spl)m5-HLH and Hes2

DIOPT Version :9

• Sequence 1: NP_524511.1
• Gene: E(spl)m5-HLH / 43158
• FlyBaseID: FBgn0002631
• Length: 178
• Species: Drosophila melanogaster
• Sequence 2: NP_001288734.1
• Gene: Hes2 / 15206
• MGIID: 1098624
• Length: 157
• Species: Mus musculus
• Alignment Length: 158
• Identity: 46/158 - (29%)
• Similarity: 78/158 - (49%)
• Gaps: 20/158 - (12%)

  Fly    23 KPLLERQRRARMNKCLDTLKTLVAEFQGDDA--ILRMDKAEMLEAALVFMRKQVVKQQAPVSPLP 85
            |||||::||||:|:.|..||.||....|.:.  ..:::||::||..:.|:::|.....:..:|.|
Mouse    18 KPLLEKRRRARINESLSQLKGLVLPLLGAETSRSSKLEKADILEMTVRFLQEQPATLYSSAAPGP 82

  Fly    86 MDSFKNGYMNAVSEISRVMACTPAMSVDVGKTVMTHLGVEFQRMLQADQVQTSVTTSTPRPLSPA 150
            ::|:..||...::.::||:.....:...|...::.||.   ||.:..|      :.|...|.:||
Mouse    83 LNSYLEGYRACLARLARVLPACSVLEPAVSARLLEHLR---QRTVSDD------SPSLTLPPAPA 138

  Fly   151 SSGYHSDNEDSQSAASPKPVEETMWRPW 178
                     .:.|...|.|....:||||
Mouse   139 ---------PAPSPPVPPPGSSGLWRPW 157

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m5-HLH	NP_524511.1	HLH	20..72	CDD:238036	21/50 (42%)
		ORANGE	87..131	CDD:128787	10/43 (23%)
Hes2	NP_001288734.1	bHLH_SF	10..73	CDD:381792	22/54 (41%)
		ORANGE	85..123	CDD:128787	9/40 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..157		10/47 (21%)
		WRPW motif	154..157		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830889
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	74	1.000	Inparanoid score	I5264
Isobase	1	0.950	-	0	Normalized mean entropy	S5317
OMA	1	1.010	-	-		QHG47782
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000785
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.850