Protein Alignment E(spl)m5-HLH and LOC1280363

DIOPT Version :10

• Sequence 1: NP_524511.1
• Gene: E(spl)m5-HLH / 43158
• FlyBaseID: FBgn0002631
• Length: 178
• Species: Drosophila melanogaster
• Sequence 2: XP_061513999.1
• Gene: LOC1280363 / 1280363
• VectorBaseID: AGAMI1_006996
• Length: 246
• Species: Anopheles gambiae
• Alignment Length: 226
• Identity: 70/226 - (30%)
• Similarity: 112/226 - (49%)
• Gaps: 62/226 - (27%)

  Fly    12 VSKTQHYLKVKKPLLERQRRARMNKCLDTLKTL-VAEFQGD-DAILRMDKAEMLEAALVFMRKQV 74
            :|:|..|.||.||:|||:||||:|:|||.||.| |:..|.: :.:.:::||::||..:..:.|..
Mosquito    24 LSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVRHLHKLR 88

  Fly    75 VKQQAPVSP-LPMDSFKNGYMNAVSEISRVMACTPAMSVDVGKTVMTHLGVEFQRMLQADQ---- 134
            .:|:...:| |..|.|:.|:.:|.:|:||.:|.||.:.:.:|..:|||||   .|:...|:
Mosquito    89 RQQRLAANPVLDADRFRAGFTHAANEVSRCLASTPGVDIKLGTKLMTHLG---HRLNDLDKVSPL 150

  Fly   135 ---VQTSVTTSTPR---------PLSP-----ASSG-------------YHSDNED---SQSAAS 166
               |::|.::||..         |:||     :|||             |.|:...   ..:..|
Mosquito   151 SVHVESSGSSSTGNSGSSRSPSPPISPFSAASSSSGDVPMYQMPLTPQSYRSEESGLLAPSTTPS 215

  Fly   167 PKPVE-------------------ETMWRPW 178
            |.|.|                   |::||||
Mosquito   216 PNPSECDDHHHHHTGGLLKIQQSGESVWRPW 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m5-HLH	NP_524511.1	bHLH-O_ESM5_like	20..78	CDD:381486	25/59 (42%)
		ORANGE	87..131	CDD:128787	17/43 (40%)
LOC1280363	XP_061513999.1	None