Protein Alignment E(spl)m5-HLH and hes6

DIOPT Version :10

• Sequence 1: NP_524511.1
• Gene: E(spl)m5-HLH / 43158
• FlyBaseID: FBgn0002631
• Length: 178
• Species: Drosophila melanogaster
• Sequence 2: XP_017949954.1
• Gene: hes6 / 100126814
• XenbaseID: XB-GENE-1018104
• Length: 195
• Species: Xenopus tropicalis
• Alignment Length: 186
• Identity: 48/186 - (25%)
• Similarity: 87/186 - (46%)
• Gaps: 34/186 - (18%)

  Fly    21 VKKPLLERQRRARMNKCLDTLKTLVA--EFQGDDAILRMDKAEMLEAALVFMRKQVVKQQAPVSP 83
            ::|||:|::||||:|:.|..|:.:::  |||.     :|:.||:||..:..:.:.:..:.|....
 Frog    16 MRKPLVEKRRRARINESLQDLRGILSDTEFQS-----KMENAEVLELTVKRVERILRNRTAEADR 75

  Fly    84 LPMDS---FKNGYMNAVSEISRVMACTPAMSVDVGKTVMTHLGVEFQRMLQA---DQVQTSVTTS 142
            |..::   |..||:..:.|:...::..|.:...:...::.|| :|...:.:.   |.|...:..|
 Frog    76 LQREASERFAAGYIQCMHEVHTFVSSCPGIDASLAAELLNHL-LESMPLSEGSLQDLVMDVLLDS 139

  Fly   143 TPRP-------LSPASSGYHSDNEDSQ-----------SAASP--KPVEETMWRPW 178
            |...       |..:|....||.|:|:           |..:|  :|...||||||
 Frog   140 TSSEEGCGLGVLGSSSEDSCSDMEESEGEKAGMGSVQDSGRTPEIQPPTPTMWRPW 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m5-HLH	NP_524511.1	bHLH-O_ESM5_like	20..78	CDD:381486	19/58 (33%)
		ORANGE	87..131	CDD:128787	8/46 (17%)
hes6	XP_017949954.1	bHLH_SF	16..69	CDD:469605	19/57 (33%)
		Hairy_orange	83..122	CDD:462193	8/39 (21%)