Protein Alignment E(spl)m3-HLH and HES7

DIOPT Version :10

• Sequence 1: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: XP_054173538.1
• Gene: HES7 / 84667
• HGNCID: 15977
• Length: 265
• Species: Homo sapiens
• Alignment Length: 91
• Identity: 31/91 - (34%)
• Similarity: 53/91 - (58%)
• Gaps: 4/91 - (4%)

  Fly    13 KVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRKLKQRGGLSLQ 77
            |::|||:|::||.|||:.|::|:.|::|..:.:.....:||||:|||..|.::|   :|..:...
Human    49 KMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLR---ERSRVEPP 110

  Fly    78 GVVA-GVGSPPTSTSTAHVESFRSGY 102
            ...| ||...|...:.|....:.||:
Human   111 AAAAPGVPRSPVQDAEALASCYLSGF 136

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m3-HLH	NP_524509.2	bHLH-O_ESMB_like	5..71	CDD:381584	23/57 (40%)
		ORANGE	96..136	CDD:128787	2/7 (29%)
HES7	XP_054173538.1	bHLH-O_HES7	48..108	CDD:381468	24/61 (39%)