Protein Alignment E(spl)m3-HLH and hes6.2

DIOPT Version :10

• Sequence 1: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_001072210.1
• Gene: hes6.2 / 779656
• XenbaseID: XB-GENE-479404
• Length: 189
• Species: Xenopus tropicalis
• Alignment Length: 214
• Identity: 62/214 - (28%)
• Similarity: 96/214 - (44%)
• Gaps: 43/214 - (20%)

  Fly    12 RKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRKLKQRGGLSL 76
            ||:.|||:|||||.|||.||:.||:.:::....:   .::||||||||:||.|::.:::.
 Frog    18 RKLRKPLIERKRRERINTCLEQLKETVIKAFHLD---QSKLEKADILEMTVRHLQNIQKS----- 74

  Fly    77 QGVVAGVGSPPTSTSTAHVESFRSGYVHAADQITQVLLQTQQTDEIGRKIMKFLSTRLIELQTQL 141
                ...|.|...:..|. :.|.:||:....::..:||.....|..       |..||:
 Frog    75 ----KSTGEPSQGSVDAQ-QRFSTGYIQCMHELHSLLLTCDWMDPA-------LGARLL------ 121

  Fly   142 LQQQQQQQQHQQQQIPQSSGRLAFPLLGGYGPAAAAAAISYSSFLTSKDELIDVTSVDGNALSET 206
                    .|..:.:|:..||.||.:....|......:.|.|      |...:.|||..:  |:.
 Frog   122 --------NHLLKSLPRPEGRTAFLIQDYEGDTGRTMSPSLS------DCEAEQTSVPLH--SDV 170

  Fly   207 ASVSSQES-GASEPVWRPW 224
            |...:|.| ..|..:||||
 Frog   171 AQGKTQCSLLRSLQMWRPW 189

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m3-HLH	NP_524509.2	bHLH-O_ESMB_like	5..71	CDD:381584	28/58 (48%)
		ORANGE	96..136	CDD:128787	9/39 (23%)
hes6.2	NP_001072210.1	bHLH_O_HES	25..75	CDD:381416	23/61 (38%)
		Hairy_orange	90..129	CDD:462193	10/59 (17%)