Protein Alignment E(spl)m3-HLH and hes7

DIOPT Version :10

• Sequence 1: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_001039166.1
• Gene: hes7 / 733997
• XenbaseID: XB-GENE-876465
• Length: 178
• Species: Xenopus tropicalis
• Alignment Length: 231
• Identity: 55/231 - (23%)
• Similarity: 85/231 - (36%)
• Gaps: 83/231 - (35%)

  Fly    11 YRKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRKLK---QRG 72
            :||::|||:||:||.|||..|:.|:..:.:.|:.|.....::|||:|||.||..::..|   |.|
 Frog    13 HRKLLKPLVERRRRERINNSLEKLRIFLSQALKSEKLKNPKVEKAEILECTVQFLQSSKLVPQDG 77

  Fly    73 GLSLQGVVAGVGSPPTSTSTAHVESFRSGYVHAADQITQVLLQTQQTD-EIGRKIMKFLSTRLIE 136
            .:..:|                   ::||:.|..:  |.:.....:.| .:..|  .|||
 Frog    78 DVGNKG-------------------YQSGFQHCLE--TALHFMNSKPDLNVATK--DFLS----- 114

  Fly   137 LQTQLLQQQQQQQQHQQQQIPQSSGRLAFPLLGGYGPAAAA----------AAISYSSFLTSKDE 191
                          ||               |..|.|.|.|          .:|.|..
 Frog   115 --------------HQ---------------LSSYKPPAEAWSPTDTPKPTPSIGYQD------- 143

  Fly   192 LIDVTSVDGNALSETAS---VSSQESGASEPVWRPW 224
              ....:..|.:|.:.:   |..|.|..:...||||
 Frog   144 --SAPHLSSNTISVSPTKTLVDGQFSPQTFQTWRPW 177

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m3-HLH	NP_524509.2	bHLH-O_ESMB_like	5..71	CDD:381584	25/62 (40%)
		ORANGE	96..136	CDD:128787	9/40 (23%)
hes7	NP_001039166.1	bHLH-O_HES7	14..74	CDD:381468	25/59 (42%)
		Hairy_orange	84..121	CDD:462193	12/74 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	122..147		5/33 (15%)
		WRPW motif. /evidence=ECO:0000255	174..177		2/2 (100%)