Protein Alignment E(spl)m3-HLH and hes5.7

DIOPT Version :10

• Sequence 1: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_001037989.1
• Gene: hes5.7 / 733782
• XenbaseID: XB-GENE-5922592
• Length: 148
• Species: Xenopus tropicalis
• Alignment Length: 219
• Identity: 47/219 - (21%)
• Similarity: 79/219 - (36%)
• Gaps: 86/219 - (39%)

  Fly     7 KTYQYRKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHV-TRLEKADILELTVDHMRKLKQ 70
            |:...||:.||::|:.||.|||..::.|:.|:.:  :.|..|: ::.|||||||:.|..   |:|
 Frog    15 KSQGIRKMRKPVVEKMRRDRINSSIEQLRMLLEK--EFEKHHLPSKPEKADILEVAVSF---LQQ 74

  Fly    71 RGGLSLQGVVAGVGSPPTSTSTAHVESFRSGYVHAADQITQVLLQTQQTDEIGRKIMKFLSTRLI 135
            |                  .:|.:.:|  ...||..|. ::.|..:.|..|..:|.:
 Frog    75 R------------------MATKYAQS--DSPVHMEDH-SRYLQDSLQFPEFSKKFL-------- 110

  Fly   136 ELQTQLLQQQQQQQQHQQQQIPQSSGRLAFPLLGGYGPAAAAAAISYSSFLTSKDELIDVTSVDG 200
                        ...|:...:..|.     ||
 Frog   111 ------------HSFHEDHSVTVSP-----PL--------------------------------- 125

  Fly   201 NALSETASVSSQESGASEPVWRPW 224
            :.|.:|.: ..:...||:.:||||
 Frog   126 SPLYQTPT-KCKTPWASKVLWRPW 148

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m3-HLH	NP_524509.2	bHLH-O_ESMB_like	5..71	CDD:381584	24/64 (38%)
		ORANGE	96..136	CDD:128787	8/39 (21%)
hes5.7	NP_001037989.1	bHLH-O_HES5	21..75	CDD:381467	22/58 (38%)