Protein Alignment E(spl)m3-HLH and hes5.2

DIOPT Version :9

• Sequence 1: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_001037974.1
• Gene: hes5.2 / 733755
• XenbaseID: XB-GENE-876635
• Length: 158
• Species: Xenopus tropicalis
• Alignment Length: 215
• Identity: 54/215 - (25%)
• Similarity: 89/215 - (41%)
• Gaps: 79/215 - (36%)

  Fly    13 KVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRKLKQRGGLSLQ 77
            |:.||::|:.||.|||..::.||.|:.....::..:| :||||||||:||.::|:      .:||
 Frog    20 KLRKPVVEKMRRDRINSSIEQLKGLLETVFHKQQPNV-KLEKADILEMTVTYLRQ------QTLQ 77

  Fly    78 GVVAGVGSPPTSTSTAHVESFRSGYVHAADQITQVLLQTQQTDEIGR---KIMKFLSTRLIELQT 139
                                .:|...|..|      :|....|...|   :::.|||.
 Frog    78 --------------------IKSEIPHNND------IQMDYKDGYSRCFEEVIDFLSL------- 109

  Fly   140 QLLQQQQQQQQHQQQQIPQSSGRLAFPLLGGYGPAAAAAAISYSSFLTSKDELIDVTSVDGNALS 204
                       ||:|  |:::     .|:..:...|.|::||......|:              |
 Frog   110 -----------HQKQ--PETA-----KLISHFHSKATASSISSFPIRCSQ--------------S 142

  Fly   205 ETASVSSQESGASEPVWRPW 224
            :||:    .:|:|..:||||
 Frog   143 KTAN----GTGSSSSLWRPW 158

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m3-HLH	NP_524509.2	HLH	11..70	CDD:238036	24/56 (43%)
		ORANGE	96..136	CDD:128787	9/42 (21%)
hes5.2	NP_001037974.1	bHLH-O_HES5	20..77	CDD:381467	24/63 (38%)
		ORANGE	90..128	CDD:128787	10/62 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1011
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000