Protein Alignment E(spl)m3-HLH and hey1

DIOPT Version :9

• Sequence 1: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_997726.1
• Gene: hey1 / 58008
• ZFINID: ZDB-GENE-000607-70
• Length: 317
• Species: Danio rerio
• Alignment Length: 266
• Identity: 65/266 - (24%)
• Similarity: 99/266 - (37%)
• Gaps: 53/266 - (19%)

  Fly    10 QYRKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRKLKQRGGL 74
            |.||..:.::|::||.|||..|.:|:.|:....:::|.  .:||||:||::||||::.|...||.
Zfish    47 QARKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHAAGGK 109

  Fly    75 ------SLQGVVAGVGSPPTSTSTAHVESFRSGY-------VHAADQITQVLLQTQQTDEIGRKI 126
                  :|.....|:|.......||...|...|.       :.....:.....|.:....:|...
Zfish   110 GYFDAHALAMDYRGLGFRECLAETARYLSIIEGLDNTDPLRIRLVSHLNSYASQREAHSGLGHLA 174

  Fly   127 M-KFLSTRLIELQTQLLQQQQQQQ-------------------QHQQQQIPQSSGRLAFPLL--- 168
            . ....|....|...||.||||||                   .......|.:..||:..::
Zfish   175 WGSAFGTPPSHLAHHLLLQQQQQQGAPLARSTSSPPSSNSSSPSSSSPSAPSTEPRLSGTVISEA 239

  Fly   169 GGYGPAAAAAAISYSSFLT-------SKDELIDVTSVDG--NALSETASVSSQESGASEP----- 219
            |..||.....:.|....||       |...|..::|:..  ..||....:|....|.:.|
Zfish   240 GQTGPLRVPPSTSLPPGLTPPTASKLSPPLLTSLSSLSAFPFPLSAFPLLSPSSLGPATPSSSLG 304

  Fly   220 -VWRPW 224
             .:|||
Zfish   305 KPYRPW 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m3-HLH	NP_524509.2	HLH	11..70	CDD:238036	23/58 (40%)
		ORANGE	96..136	CDD:128787	5/47 (11%)
hey1	NP_997726.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..59		4/11 (36%)
		HLH	49..106	CDD:238036	23/58 (40%)
		ORANGE	119..165	CDD:128787	7/45 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	193..264		15/70 (21%)
		YRPW motif	307..310		1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573628
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740