Protein Alignment E(spl)m3-HLH and hey1

DIOPT Version :10

• Sequence 1: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_997726.2
• Gene: hey1 / 58008
• ZFINID: ZDB-GENE-000607-70
• Length: 318
• Species: Danio rerio
• Alignment Length: 281
• Identity: 65/281 - (23%)
• Similarity: 103/281 - (36%)
• Gaps: 82/281 - (29%)

  Fly    10 QYRKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRKLKQRGGL 74
            |.||..:.::|::||.|||..|.:|:.|:....:::|.  .:||||:||::||||::.|...||.
Zfish    47 QARKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHAAGGK 109

  Fly    75 ------SLQGVVAGVGSPPTSTSTAHVESFRSGYVHAADQITQVLLQTQQTDEIGRKIMKFLSTR 133
                  :|.....|:|.......||...|...|              ...||.:..:::..|::.
Zfish   110 GYFDAHALAMDYRGLGFRECLAETARYLSIIEG--------------LDNTDPLRIRLVSHLNSY 160

  Fly   134 LIELQTQ-----------------------LLQQQQQQQ-------------------QHQQQQI 156
            ..:.:..                       |||||||||                   .......
Zfish   161 ASQREAHSGLGHLAWGSAFGTPPSHLAHHLLLQQQQQQQGAPLARSTSSPPSSNSSSPSSSSPSA 225

  Fly   157 PQSSGRLAFPLL---GGYGPAAAAAAISYSSFLT-------SKDELIDVTSVDG--NALSETASV 209
            |.:..||:..::   |..||.....:.|....||       |...|..::|:..  ..||....:
Zfish   226 PSTEPRLSGTVISEAGQTGPLRVPPSTSLPPGLTPPTASKLSPPLLTSLSSLSAFPFPLSAFPLL 290

  Fly   210 SSQESGASEP------VWRPW 224
            |....|.:.|      .:|||
Zfish   291 SPSSLGPATPSSSLGKPYRPW 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m3-HLH	NP_524509.2	bHLH-O_ESMB_like	5..71	CDD:381584	24/60 (40%)
		ORANGE	96..136	CDD:128787	5/39 (13%)
hey1	NP_997726.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..59		4/11 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..265		15/70 (21%)
		YRPW motif	308..311		1/2 (50%)