Protein Alignment E(spl)m3-HLH and Hes6

DIOPT Version :9

• Sequence 1: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_062352.1
• Gene: Hes6 / 55927
• MGIID: 1859852
• Length: 224
• Species: Mus musculus
• Alignment Length: 227
• Identity: 61/227 - (26%)
• Similarity: 93/227 - (40%)
• Gaps: 42/227 - (18%)

  Fly    12 RKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHV-TRLEKADILELTVDHMRKLKQRGGLS 75
            ||..|||:|:|||||||:.|.:|:.|:.      |..| .:||.|::|||||..
Mouse    26 RKARKPLVEKKRRARINESLQELRLLLA------GTEVQAKLENAEVLELTVRR----------- 73

  Fly    76 LQGVVAGVGSPPTSTSTAHVESFRSGYVHAADQITQVLLQTQQTDEIGRKIMKFLSTRLIELQTQ 140
            :||.:.|.............|.|.:||:....::...:...|..|          :|...||...
Mouse    74 VQGALRGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAID----------ATVSAELLNH 128

  Fly   141 LLQQQQQQQQHQQQQ--------IPQSSGRLAFPLLGGYGPAAAAAAISYSSFLTSKDELIDVTS 197
            ||:....::....|.        :|..|||.::| .||...:..::.......|.|..|.|....
Mouse   129 LLESMPLREGSSFQDLLGDSLAGLPGGSGRSSWP-PGGSPESPLSSPPGPGDDLCSDLEEIPEAE 192

  Fly   198 V-----DGNALSETASVSSQESGASEPVWRPW 224
            :     :|..|..|:..|...:..::.|||||
Mouse   193 LNRVPAEGPDLVSTSLGSLTAARRAQSVWRPW 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m3-HLH	NP_524509.2	HLH	11..70	CDD:238036	26/58 (45%)
		ORANGE	96..136	CDD:128787	7/39 (18%)
Hes6	NP_062352.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..31		2/4 (50%)
		bHLH_SF	24..81	CDD:412148	28/71 (39%)
		Hairy_orange	96..134	CDD:400076	10/47 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	146..209		14/63 (22%)
		WRPW motif	221..224		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830823
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.700