Protein Alignment E(spl)m3-HLH and her13

DIOPT Version :10

• Sequence 1: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_001017901.1
• Gene: her13 / 550600
• ZFINID: ZDB-GENE-050228-1
• Length: 224
• Species: Danio rerio
• Alignment Length: 237
• Identity: 62/237 - (26%)
• Similarity: 95/237 - (40%)
• Gaps: 61/237 - (25%)

  Fly    12 RKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRKLKQRGGLSL 76
            ||..||::|:|||||||:.|.||:.|:.     ..:..|::|.|::|||||..:..:.|.
Zfish    25 RKTRKPIVEKKRRARINESLQDLRTLLT-----NNDLQTKMENAEVLELTVKRVESILQS----- 79

  Fly    77 QGVVAGVGSPPTSTSTAHV-ESFRSGYVHAADQITQVLLQTQQTDEIGRKIMKFLST------RL 134
                   .|..|.|.|... |.|.:||:...                 .::..|:||      |:
Zfish    80 -------RSQETGTVTQEASERFAAGYIQCM-----------------HEVHTFVSTCPGIEARV 120

  Fly   135 -IELQTQLLQQQQQQQQHQQQQI------PQSSGRLAFPLLGGYGPAAAAAAISYSS-----FLT 187
             .||...||:.....:.|..:.|      |.|||.   ....|.........:|..|     ||:
Zfish   121 AAELLNHLLESMPLNENHLHEMIKDLISEPSSSGD---SWQSGEAQNPGRHCVSGMSSELPQFLS 182

  Fly   188 SK--DEL---IDVTSVDGNALSETASVSSQESGASEPVWRPW 224
            :.  |:|   :|.|..:..:.|...::.......|:.:||||
Zfish   183 NPFCDDLCSDLDETETEERSASAEDTLDFSMVTHSKFMWRPW 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m3-HLH	NP_524509.2	bHLH-O_ESMB_like	5..71	CDD:381584	24/58 (41%)
		ORANGE	96..136	CDD:128787	8/46 (17%)
her13	NP_001017901.1	bHLH_SF	23..80	CDD:469605	25/71 (35%)
		Hairy_orange	94..133	CDD:462193	11/55 (20%)