Protein Alignment E(spl)m3-HLH and Helt

DIOPT Version :10

• Sequence 1: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: XP_008769494.1
• Gene: Helt / 498633
• RGDID: 1564073
• Length: 241
• Species: Rattus norvegicus
• Alignment Length: 209
• Identity: 50/209 - (23%)
• Similarity: 82/209 - (39%)
• Gaps: 41/209 - (19%)

  Fly     5 MSKTYQYRK---VMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMR 66
            ||...:.||   |...::|::||.|||:||::|...:...|.::..  .:||||:|||:||.::|
  Rat     1 MSDRLKERKRTPVSHKVIEKRRRDRINRCLNELGKTVPMALAKQSS--GKLEKAEILEMTVQYLR 63

  Fly    67 KLKQRGGLSLQGVVAGVGSPPTSTSTAHVESFRSGYVHAADQITQVL-----LQTQQTDEIGRKI 126
                    :|.......|.............|..||......:...|     ::|:.|..  .:|
  Rat    64 --------ALHSADFPRGREKAELLAEFANYFHYGYHECMKNLVHYLTTVERMETKDTKY--ARI 118

  Fly   127 MKFLSTRL---------------IELQTQLLQQQQQQQQHQQQQ---IPQSSGRLAFPLLGGYGP 173
            :.||.::.               .:...||.....:...|...:   .||.:...:||...|
  Rat   119 LAFLQSKARLGAEPAFPPLSLPEPDFSYQLHPAGPEFPGHSPGEATVFPQGATPGSFPWPPG--- 180

  Fly   174 AAAAAAISYSSFLT 187
            ||.:.|:.|.|..|
  Rat   181 AARSPALPYLSSAT 194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m3-HLH	NP_524509.2	bHLH-O_ESMB_like	5..71	CDD:381584	25/68 (37%)
		ORANGE	96..136	CDD:128787	9/59 (15%)
Helt	XP_008769494.1	bHLH-O_HELT	14..69	CDD:381414	21/64 (33%)
		Hairy_orange	86..127	CDD:462193	9/42 (21%)
		DUF1373	129..>213	CDD:462093	14/69 (20%)