Protein Alignment E(spl)m3-HLH and hes1

DIOPT Version :9

• Sequence 1: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_001011194.1
• Gene: hes1 / 496617
• XenbaseID: XB-GENE-487995
• Length: 267
• Species: Xenopus tropicalis
• Alignment Length: 255
• Identity: 71/255 - (27%)
• Similarity: 115/255 - (45%)
• Gaps: 60/255 - (23%)

  Fly    10 QYRKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRKLKQRGGL 74
            ::||..||::|::||||||:.|..||.|:::.|:::....::||||||||:||.|:|.|::
 Frog    33 EHRKSSKPIMEKRRRARINESLGQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQR---- 93

  Fly    75 SLQGVVAGVGSPPTSTSTAHVESFRSGYVHAADQITQVLLQTQ--QTDEIGRKIMKFLSTRLIEL 137
             :|...|      .||..:.:..:|:|:....:::|:.|...:  .||         :.|||:..
 Frog    94 -VQMTAA------LSTDPSVLGKYRAGFSECMNEVTRFLSTCEGVNTD---------VRTRLLGH 142

  Fly   138 QTQLLQQQQQQQQHQQQQIPQSSG---RLAFPL--LGGYGPAAAAAAIS-------------YSS 184
            ....:.|........|.|||.::.   ....||  |.|..|.::.|.|:             |..
 Frog   143 LANCMNQINAMNYPTQPQIPAAAAPHPAYGQPLVQLQGAAPQSSPAPIACKMGGPPVEAAKVYGG 207

  Fly   185 F-------------LTS-----KDELIDV--TSVDGNALSETASVSSQESGASEPVWRPW 224
            |             :|:     ...:|.|  .|..|.||..:.|.|...|..::.|||||
 Frog   208 FQLVPAPDGQFAFLITNPAFPHNGSVIPVYTNSNVGTALPPSVSPSVMPSVTADSVWRPW 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m3-HLH	NP_524509.2	HLH	11..70	CDD:238036	29/58 (50%)
		ORANGE	96..136	CDD:128787	9/41 (22%)
hes1	NP_001011194.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..45		5/11 (45%)
		bHLH-O_HES1_4	33..95	CDD:381465	29/66 (44%)
		Hairy_orange	110..148	CDD:369405	9/46 (20%)
		WRPW motif. /evidence=ECO:0000255	264..267		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000785
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010