Protein Alignment E(spl)m3-HLH and cwo

DIOPT Version :9

• Sequence 1: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_524775.1
• Gene: cwo / 44669
• FlyBaseID: FBgn0259938
• Length: 698
• Species: Drosophila melanogaster
• Alignment Length: 244
• Identity: 53/244 - (21%)
• Similarity: 91/244 - (37%)
• Gaps: 69/244 - (28%)

  Fly     6 SKTYQYRKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRKLKQ 70
            :||.:...:...::|::||.|:|.||.||..|:....|::|.  .|:||.:|:|:.:.|::.|:
  Fly    57 NKTSRQDPLSHRIIEKRRRDRMNSCLADLSRLIPPQYQRKGR--GRIEKTEIIEMAIRHLKHLQ- 118

  Fly    71 RGGLSLQGVVAGVGSPPTSTSTAHVESFRSGYVHAADQITQVLLQTQQTD----EIGR------- 124
                              |........:||||:....:..:.|......|    .:||
  Fly   119 ------------------SECQQKESDYRSGYMDCMKEAAKFLYDVHMQDFCHRLLGRLQEHIDE 165

  Fly   125 --KIMKFLSTR----------------------LIELQTQLLQQQQQQQQHQQ--QQIPQSSGRL 163
              |...:.|||                      |..|: .:|.......:|.|  ..:...|.|.
  Fly   166 MFKTDCYKSTRSCHMPDNVSASSGSPHQAYHPPLCHLR-DMLATSASDVEHSQDHNDVKDLSFRN 229

  Fly   164 AFPLLGGYGPAAAAAAISYSSFLTSKDELIDVTSVDGNALSETASVSSQ 212
            ....|.....||||||::.::          |...:|::.:..|.|.|:
  Fly   230 HLNQLQRSQQAAAAAAVAAAA----------VAVANGSSPASNAGVDSK 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m3-HLH	NP_524509.2	HLH	11..70	CDD:238036	19/58 (33%)
		ORANGE	96..136	CDD:128787	13/74 (18%)
cwo	NP_524775.1	HLH	66..118	CDD:306515	18/53 (34%)
		ORANGE	126..168	CDD:128787	8/41 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438365
Domainoid	1	1.000	45	1.000	Domainoid score	I4621
eggNOG	1	0.900	-	-		E1_KOG4304
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840