DRSC/TRiP Functional Genomics Resources

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Protein Alignment E(spl)m3-HLH and hes4

DIOPT Version :9

Sequence 1:NP_524509.2 Gene:E(spl)m3-HLH / 43156 FlyBaseID:FBgn0002609 Length:224 Species:Drosophila melanogaster
Sequence 2:NP_988870.1 Gene:hes4 / 394465 XenbaseID:XB-GENE-487830 Length:281 Species:Xenopus tropicalis


Alignment Length:261 Identity:70/261 - (26%)
Similarity:118/261 - (45%) Gaps:58/261 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 QYRKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRKLKQRGGL 74
            ::||..||::|::||||||:.|..||.|:::.|:::....::||||||||:||.|:|.|::    
 Frog    33 EHRKSSKPIMEKRRRARINESLGQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNLQR---- 93

  Fly    75 SLQGVVAGVGSPPTSTSTAHVESFRSGYVHAADQITQVLLQTQQTD-EIGRKIMKFLSTRLIELQ 138
             :|...|....|..      :..:|:|:....:::|:.|...:..: |:..:::..||:.|.::.
 Frog    94 -VQMTAALTADPSV------LGKYRAGFNECMNEVTRFLSTCEGVNTEVRTRLLGHLSSCLGQIV 151

  Fly   139 TQLLQQQQQQQQHQQQQIPQSSGRLAFPLLGGYGPAAA--------------------AAAISYS 183
            ....||....||....|:| ||.....|:.....||.|                    |..|...
 Frog   152 AMNYQQPPSSQQPLHVQLP-SSTPAPVPMPCKVNPAEAISPKVFQGGFQLVPATDGQFAFLIPNP 215

  Fly   184 SFLTSKDELI------DVTSVDGNA-----------------LSETASVSSQESGA--SEPVWRP 223
            ::.||...:|      :|||..|..                 :::..|.....:||  :|.||||
 Frog   216 AYTTSPGPVIPLYANTNVTSPGGPQSQSPVQGLTTFGHKMPHMAQAVSPLGGSTGADSAESVWRP 280

  Fly   224 W 224
            |
 Frog   281 W 281

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
E(spl)m3-HLHNP_524509.2 HLH 11..70 CDD:238036 29/58 (50%)
ORANGE 96..136 CDD:128787 8/40 (20%)
hes4NP_988870.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..44 4/10 (40%)
bHLH-O_HES1_4 33..95 CDD:381465 29/66 (44%)
Hairy_orange 110..147 CDD:369405 7/36 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 262..281 7/18 (39%)
WRPW motif. /evidence=ECO:0000255 278..281 2/2 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000785
OrthoInspector 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR10985
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
33.010

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