Protein Alignment E(spl)m3-HLH and hry

DIOPT Version :10

• Sequence 1: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_523977.2
• Gene: hry / 38995
• FlyBaseID: FBgn0001168
• Length: 337
• Species: Drosophila melanogaster
• Alignment Length: 324
• Identity: 72/324 - (22%)
• Similarity: 123/324 - (37%)
• Gaps: 129/324 - (39%)

  Fly    12 RKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRKLKQRGGLSL 76
            |:..||::|::||||||.||::||.|:::..:::....::||||||||.||.|:::|:::
  Fly    32 RRSNKPIMEKRRRARINNCLNELKTLILDATKKDPARHSKLEKADILEKTVKHLQELQRQ----- 91

  Fly    77 QGVVAGVGSPPTSTSTAHVESFRSGYVHAADQITQVL-LQTQQTDEIGRKIMKFLSTRLIELQTQ 140
            |..:.....|..      |..|::|:....:::::.. ::..|.    |::::.||..:..::|:
  Fly    92 QAAMQQAADPKI------VNKFKAGFADCVNEVSRFPGIEPAQR----RRLLQHLSNCINGVKTE 146

  Fly   141 LLQQQQQQQQ---HQQQ------------------------------------------QIPQSS 160
            |.|||:||||   |.|.                                          ::|..|
  Fly   147 LHQQQRQQQQQSIHAQMLPSPPSSPEQDSQQGAAAPYLFGIQQTASGYFLPNGMQVIPTKLPNGS 211

  Fly   161 GRLAFP-------------------LLGGYGPAAAAAAISYSSFLTSKDELIDVTSVDGNALSET 206
            ..|..|                   .|.....||||||......|.|..:.   |:..|:|.|.:
  Fly   212 IALVLPQSLPQQQQQQLLQHQQQQQQLAVAAAAAAAAAAQQQPMLVSMPQR---TASTGSASSHS 273

  Fly   207 ASVSSQESGAS---------------EPV-------------------------------WRPW 224
            ::......|:|               ||:                               ||||
  Fly   274 SAGYESAPGSSSSCSYAPPSPANSSYEPMDIKPSVIQRVPMEQQPLSLVIKKQIKEEEQPWRPW 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m3-HLH	NP_524509.2	bHLH-O_ESMB_like	5..71	CDD:381584	27/58 (47%)
		ORANGE	96..136	CDD:128787	6/40 (15%)
hry	NP_523977.2	bHLH-O_hairy_like	30..88	CDD:381483	26/55 (47%)
		ORANGE	106..141	CDD:128787	6/38 (16%)