DRSC/TRiP Functional Genomics Resources

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Protein Alignment E(spl)m3-HLH and h

DIOPT Version :9

Sequence 1:NP_524509.2 Gene:E(spl)m3-HLH / 43156 FlyBaseID:FBgn0002609 Length:224 Species:Drosophila melanogaster
Sequence 2:NP_001014577.1 Gene:h / 38995 FlyBaseID:FBgn0001168 Length:337 Species:Drosophila melanogaster


Alignment Length:324 Identity:72/324 - (22%)
Similarity:123/324 - (37%) Gaps:129/324 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 RKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRKLKQRGGLSL 76
            |:..||::|::||||||.||::||.|:::..:::....::||||||||.||.|:::|:::     
  Fly    32 RRSNKPIMEKRRRARINNCLNELKTLILDATKKDPARHSKLEKADILEKTVKHLQELQRQ----- 91

  Fly    77 QGVVAGVGSPPTSTSTAHVESFRSGYVHAADQITQVL-LQTQQTDEIGRKIMKFLSTRLIELQTQ 140
            |..:.....|..      |..|::|:....:::::.. ::..|.    |::::.||..:..::|:
  Fly    92 QAAMQQAADPKI------VNKFKAGFADCVNEVSRFPGIEPAQR----RRLLQHLSNCINGVKTE 146

  Fly   141 LLQQQQQQQQ---HQQQ------------------------------------------QIPQSS 160
            |.|||:||||   |.|.                                          ::|..|
  Fly   147 LHQQQRQQQQQSIHAQMLPSPPSSPEQDSQQGAAAPYLFGIQQTASGYFLPNGMQVIPTKLPNGS 211

  Fly   161 GRLAFP-------------------LLGGYGPAAAAAAISYSSFLTSKDELIDVTSVDGNALSET 206
            ..|..|                   .|.....||||||......|.|..:.   |:..|:|.|.:
  Fly   212 IALVLPQSLPQQQQQQLLQHQQQQQQLAVAAAAAAAAAAQQQPMLVSMPQR---TASTGSASSHS 273

  Fly   207 ASVSSQESGAS---------------EPV-------------------------------WRPW 224
            ::......|:|               ||:                               ||||
  Fly   274 SAGYESAPGSSSSCSYAPPSPANSSYEPMDIKPSVIQRVPMEQQPLSLVIKKQIKEEEQPWRPW 337

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
E(spl)m3-HLHNP_524509.2 HLH 11..70 CDD:238036 27/57 (47%)
ORANGE 96..136 CDD:128787 6/40 (15%)
hNP_001014577.1 HLH 29..88 CDD:238036 26/55 (47%)
ORANGE 106..141 CDD:128787 6/38 (16%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45438343
Domainoid 1 1.000 45 1.000 Domainoid score I4621
eggNOG 1 0.900 - - E1_KOG4304
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000785
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR10985
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
65.840

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