Protein Alignment E(spl)m3-HLH and hes6

DIOPT Version :9

• Sequence 1: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_919381.2
• Gene: hes6 / 373116
• ZFINID: ZDB-GENE-030828-5
• Length: 226
• Species: Danio rerio
• Alignment Length: 236
• Identity: 56/236 - (23%)
• Similarity: 99/236 - (41%)
• Gaps: 52/236 - (22%)

  Fly    12 RKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRKLKQRGGLSL 76
            ||..|||:|:|||||||:.|.:|:.|:.:...|     .::|.|::||:||..           :
Zfish    20 RKTRKPLVEKKRRARINESLQELRLLLADPDAQ-----VKMENAEVLEMTVKR-----------V 68

  Fly    77 QGVVAGVGSPPTSTSTAHVESFRSGYVHAADQITQVLLQTQQTD-EIGRKIMKFLSTRLIELQTQ 140
            :.::........|.:....|.|.:||:....::...:......| .|...::..|      |:..
Zfish    69 ESILQNKAKEADSVNREANERFAAGYIQCMHEVHTFVSSCPGIDATIAADLLNHL------LECM 127

  Fly   141 LLQQQQQQQQHQQQQIPQSS------GRLAFPLLGGYGPAAA---AAAISYSSFLTSKDEL---I 193
            .|..:::.|......|..|:      |..|:..|...|.:.|   ::|:|.:...||.|::   :
Zfish   128 PLNDEERFQDILSDLISDSNNSGTWPGEAAYATLSPGGTSVANGGSSALSPAPSTTSSDDICSDL 192

  Fly   194 DVTSVDGNALSETASVSSQESGASEPV----------WRPW 224
            |.|..:.:.:       |.::|...||          ||||
Zfish   193 DDTDTEHSRI-------SVDAGDQAPVVPTLYTNKSIWRPW 226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m3-HLH	NP_524509.2	HLH	11..70	CDD:238036	23/57 (40%)
		ORANGE	96..136	CDD:128787	7/40 (18%)
hes6	NP_919381.2	HLH	18..75	CDD:238036	23/70 (33%)
		Hairy_orange	90..128	CDD:284859	7/43 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573602
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	92	1.000	Inparanoid score	I5073
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1483774at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	6	5.760