Protein Alignment E(spl)m3-HLH and bhlhe40

DIOPT Version :10

• Sequence 1: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_997844.2
• Gene: bhlhe40 / 324413
• ZFINID: ZDB-GENE-030131-3133
• Length: 403
• Species: Danio rerio
• Alignment Length: 229
• Identity: 69/229 - (30%)
• Similarity: 106/229 - (46%)
• Gaps: 54/229 - (23%)

  Fly     4 EMSK-TYQYRKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRK 67
            |.|| ||   |:...|:|:|||.|||:|:..||||:.|.|:.  ..:..||||.:||||:.|::.
Zfish    44 EDSKDTY---KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTLKHVKA 103

  Fly    68 L------KQRGGLSLQ-GVVAG-VGSPPTSTSTAHVESFRSGYVHAADQITQVLLQTQQTDEIGR 124
            |      :|:..:||| |:..| .|:.|:..|.   |.||||:...|.::.| .|..|:|
Zfish   104 LNNLLEQQQQKIISLQNGLQIGEQGNGPSENSE---EMFRSGFHLCAKEVLQ-FLANQET----- 159

  Fly   125 KIMKFLST-RLIELQTQLLQQQQQQQQHQQQQIPQSSGRLAFPLLGGYGPAAAAAAISYSSFLTS 188
              |:.|:| .:||...::..:..|.....:...|.|..:.:.....|..|.||
Zfish   160 --MRDLTTAHIIEHLQKVASELIQSPPSPRLDEPASKAQESREKPSGLQPKAA------------ 210

  Fly   189 KDELIDVTSVDGNA------LSETASVSSQESGA 216
                      :|:|      :..|...||::||:
Zfish   211 ----------EGHAKNCVPVIQRTYPHSSEQSGS 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m3-HLH	NP_524509.2	bHLH-O_ESMB_like	5..71	CDD:381584	30/72 (42%)
		ORANGE	96..136	CDD:128787	13/40 (33%)
bhlhe40	NP_997844.2	bHLH-O_DEC1	37..126	CDD:381592	36/86 (42%)
		Hairy_orange	138..177	CDD:462193	14/46 (30%)