Protein Alignment E(spl)m3-HLH and her8a

DIOPT Version :9

• Sequence 1: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_955918.3
• Gene: her8a / 323656
• ZFINID: ZDB-GENE-030131-2376
• Length: 221
• Species: Danio rerio
• Alignment Length: 231
• Identity: 69/231 - (29%)
• Similarity: 103/231 - (44%)
• Gaps: 47/231 - (20%)

  Fly    12 RKVMKPLLERKRRARINKCLDDLKDLMVEC--LQQEGEHVTRLEKADILELTVDHMRKLKQRGGL 74
            ||:.|||:|:|||.|||..|:.||.:||:.  |.|     ::|||||:||:||.||..|::..|
Zfish    20 RKLRKPLIEKKRRERINSSLEQLKGIMVDAYNLDQ-----SKLEKADVLEITVQHMENLQRGHG- 78

  Fly    75 SLQGVVAGVGSPPTSTSTAHVESFRSGYVHAADQITQVLLQTQQTDE-IGRKIMKFLSTRLIELQ 138
              ||   |..||.|...:.  :.:.|||:....::..:||.....|: :|.:::..|...|..:.
Zfish    79 --QG---GSNSPGTGFESR--QRYSSGYIQCMHEVHNLLLSCPGMDKTLGARLLNHLLKSLPHIS 136

  Fly   139 TQLLQQQQQQQQHQQQQIP---QSSGRLA-FPLLGGYGPAAAAAAISYSSFLTSKDELIDVTS-- 197
            |:                |   .|:|..: .||.....|....:::...:.|.|.......|.
Zfish   137 TE----------------PSGTSSAGTSSPLPLSPTQSPINLPSSLQPHALLLSPSPPSSPTHSL 185

  Fly   198 VDGNALSETASVSSQESGASEP---------VWRPW 224
            |.....|...|..|.:|.||.|         :||||
Zfish   186 VRPREQSSPPSSPSPQSPASLPPFFPGVDPSMWRPW 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m3-HLH	NP_524509.2	HLH	11..70	CDD:238036	31/59 (53%)
		ORANGE	96..136	CDD:128787	9/40 (23%)
her8a	NP_955918.3	HLH	17..75	CDD:238036	31/59 (53%)
		Hairy_orange	95..133	CDD:284859	8/37 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573645
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	92	1.000	Inparanoid score	I5073
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1483774at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.860