Protein Alignment E(spl)m3-HLH and Hes2

DIOPT Version :9

• Sequence 1: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_062109.1
• Gene: Hes2 / 29567
• RGDID: 62082
• Length: 157
• Species: Rattus norvegicus
• Alignment Length: 226
• Identity: 56/226 - (24%)
• Similarity: 83/226 - (36%)
• Gaps: 91/226 - (40%)

  Fly    10 QYRKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRKLKQRGGL 74
            :.||.:|||||::||||||:.|..||.|::..|..|....::||||||||:||..:|:
  Rat    12 ELRKSLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRYSKLEKADILEMTVRFLRE------- 69

  Fly    75 SLQGVVAGVGSPPTSTST---AHVESFRSGYVHAADQITQVLLQTQQTDEIGRKIMKFLSTRLIE 136
                      .|.:..||   ..::|:..||.....::.:||......:..       :|.||:|
  Rat    70 ----------QPASVCSTEAPGSLDSYLEGYRACLARLARVLPACSVLEPA-------VSARLLE 117

  Fly   137 LQTQLLQQQQQQQQHQQQQIPQSSGRLAFPLLGGYGPAAAAAAISYSSFLTSKDELIDVTSVDGN 201
                          |.:|:                                         :|.|.
  Rat   118 --------------HLRQR-----------------------------------------TVSGG 127

  Fly   202 ALSETASVSSQESGASEPV--------WRPW 224
            ..|.|.: |:.....|.||        ||||
  Rat   128 PPSLTPA-SASAPAPSPPVPPPSSLGLWRPW 157

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m3-HLH	NP_524509.2	HLH	11..70	CDD:238036	30/58 (52%)
		ORANGE	96..136	CDD:128787	8/39 (21%)
Hes2	NP_062109.1	HLH	12..69	CDD:238036	29/56 (52%)
		ORANGE	84..128	CDD:128787	13/105 (12%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..157		10/33 (30%)
		WRPW motif	154..157		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334596
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000785
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10985
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.840