Protein Alignment E(spl)m3-HLH and Helt

DIOPT Version :9

• Sequence 1: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: XP_006509452.1
• Gene: Helt / 234219
• MGIID: 3040955
• Length: 241
• Species: Mus musculus
• Alignment Length: 209
• Identity: 50/209 - (23%)
• Similarity: 82/209 - (39%)
• Gaps: 41/209 - (19%)

  Fly     5 MSKTYQYRK---VMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMR 66
            ||...:.||   |...::|::||.|||:||::|...:...|.::..  .:||||:|||:||.::|
Mouse     1 MSDRLKERKRTPVSHKVIEKRRRDRINRCLNELGKTVPMALAKQSS--GKLEKAEILEMTVQYLR 63

  Fly    67 KLKQRGGLSLQGVVAGVGSPPTSTSTAHVESFRSGYVHAADQITQVL-----LQTQQTDEIGRKI 126
                    :|.......|.............|..||......:...|     ::|:.|..  .:|
Mouse    64 --------ALHSADFPRGREKAELLAEFANYFHYGYHECMKNLVHYLTTVERMETKDTKY--ARI 118

  Fly   127 MKFLSTRL---------------IELQTQLLQQQQQQQQH---QQQQIPQSSGRLAFPLLGGYGP 173
            :.||.::.               .:...||.....:...|   :....||.:...:||...|
Mouse   119 LAFLQSKARLGAEPTFPPLSLPEPDFSYQLHAASPEFPGHSPGEATMFPQGATPGSFPWPPG--- 180

  Fly   174 AAAAAAISYSSFLT 187
            ||.:.|:.|.|..|
Mouse   181 AARSPALPYLSSAT 194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m3-HLH	NP_524509.2	HLH	11..70	CDD:238036	23/61 (38%)
		ORANGE	96..136	CDD:128787	9/59 (15%)
Helt	XP_006509452.1	bHLH-O_HELT	14..69	CDD:381414	21/64 (33%)
		Hairy_orange	87..127	CDD:369405	9/41 (22%)
		PLN02983	<147..>213	CDD:215533	14/51 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830832
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740