Protein Alignment E(spl)m3-HLH and lin-22

DIOPT Version :9

• Sequence 1: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_500281.1
• Gene: lin-22 / 177082
• WormBaseID: WBGene00003008
• Length: 173
• Species: Caenorhabditis elegans
• Alignment Length: 141
• Identity: 41/141 - (29%)
• Similarity: 67/141 - (47%)
• Gaps: 31/141 - (21%)

  Fly    16 KPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRKLKQRGGLSLQGVV 80
            |||:|:||||||||.|..||.::::...:.....::.|||||||:.|:::::|:.....||....
 Worm    26 KPLMEKKRRARINKSLSQLKQILIQDEHKNSIQHSKWEKADILEMAVEYLQQLRSAQPCSLSPST 90

  Fly    81 AGVGSPPTSTSTAH--------VESF----RSGYVHAADQITQVLLQTQ---------------- 117
            :.:.:|||......        :.||    ...|| |..|:.|:.:.||
 Worm    91 SSISTPPTPKEEIRNIKVPLNPIASFLNPMMQQYV-AYQQLAQLSMYTQLFNNPAGVPLRADAGV 154

  Fly   118 --QTDEIGRKI 126
              |:.|:..|:
 Worm   155 TAQSPELAEKL 165

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m3-HLH	NP_524509.2	HLH	11..70	CDD:238036	24/53 (45%)
		ORANGE	96..136	CDD:128787	12/53 (23%)
lin-22	NP_500281.1	bHLH_O_HES	29..82	CDD:381416	21/52 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	65	1.000	Domainoid score	I6616
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000785
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1011
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.770