Protein Alignment E(spl)m3-HLH and Hes5

DIOPT Version :9

• Sequence 1: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: XP_006538625.3
• Gene: Hes5 / 15208
• MGIID: 104876
• Length: 415
• Species: Mus musculus
• Alignment Length: 243
• Identity: 59/243 - (24%)
• Similarity: 95/243 - (39%)
• Gaps: 70/243 - (28%)

  Fly     1 MVMEMSKTYQYRKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHV--TRLEKADILELTVD 63
            :.:||....:..::.||::|:.||.|||..::.|| |::|  |:...|.  ::||||||||:.|.
Mouse   224 VAVEMLSPKEKNRLRKPVVEKMRRDRINSSIEQLK-LLLE--QEFARHQPNSKLEKADILEMAVS 285

  Fly    64 HMRKLKQRGG----LSLQGVVAGVG-SP------PTSTSTA------HVESFRSGYVHAADQITQ 111
            :::..|...|    |.|...||... :|      ||:.:.|      | :.:..||.....:..|
Mouse   286 YLKHSKGEPGACARLLLPADVAPTARAPLMPLRLPTAFAAAAGPKSLH-QDYSEGYSWCLQEAVQ 349

  Fly   112 VLLQTQQTDEIGRKIMKFLSTRLIELQTQLLQQQQQQQQHQQQQIPQSSGRLAFPLLGGYGPAAA 176
            .|.....:|                .|.:||        :..|:.|..:.....|...|..|..|
Mouse   350 FLTLHAASD----------------TQMKLL--------YHFQRPPAPAAPAKEPPAPGAAPQPA 390

  Fly   177 AAAISYSSFLTSKDELIDVTSVDGNALSETASVSSQESGASEPVWRPW 224
            .:                      :|.:..|:||:....|. .:||||
Mouse   391 RS----------------------SAKAAAAAVSTSRQPAC-GLWRPW 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m3-HLH	NP_524509.2	HLH	11..70	CDD:238036	23/60 (38%)
		ORANGE	96..136	CDD:128787	5/39 (13%)
Hes5	XP_006538625.3	bHLH-O_HES5	236..292	CDD:381467	23/58 (40%)
		ORANGE	334..369	CDD:128787	8/58 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830904
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1011
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840