Protein Alignment E(spl)m3-HLH and her9

DIOPT Version :10

• Sequence 1: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_571948.1
• Gene: her9 / 140613
• ZFINID: ZDB-GENE-011213-1
• Length: 291
• Species: Danio rerio
• Alignment Length: 272
• Identity: 72/272 - (26%)
• Similarity: 120/272 - (44%)
• Gaps: 70/272 - (25%)

  Fly    10 QYRKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRKLKQRGGL 74
            ::||..||::|::||||||:.|..||.|:::.|:::....::||||||||:||.|:|.| ||..:
Zfish    33 EHRKSSKPIMEKRRRARINESLGQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNL-QRVQM 96

  Fly    75 SLQGVVAGVGSPPTSTSTAHVESFRSGYVHAADQITQVLLQTQQTD-EIGRKIMKFLSTRLIELQ 138
                      |...|..|..:..:|:|:....:::|:.|...:..: |:..:::..||..:.::.
Zfish    97 ----------SAALSADTNVLSKYRAGFNECMNEVTRFLSTCEGVNTEVRSRLLNHLSGCMGQMM 151

  Fly   139 TQLLQQQQQQQQ-------HQQ------------------------------QQIPQSSGRLAF- 165
            .....|....||       |.|                              |.:|.:.|:.||
Zfish   152 AMNYPQPAPAQQAHLAQPLHVQLPSTLPINGASMGSKLSPSEAVSPKVFGGFQLVPATDGQFAFL 216

  Fly   166 -----------PLLGGYGPAAA-----AAAISYSSFLTSKDELIDVTSVDG--NALSETASVSSQ 212
                       |::..|..|:.     |:.:..||..|....:..:||..|  .|:|.....:..
Zfish   217 IPNPAFASATTPVIPLYANASVPVTVNASPVQASSAPTVASPVQGMTSFSGVPQAVSPVGVSAGA 281

  Fly   213 ESGASEPVWRPW 224
            ||  :|||||||
Zfish   282 ES--NEPVWRPW 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m3-HLH	NP_524509.2	bHLH-O_ESMB_like	5..71	CDD:381584	29/60 (48%)
		ORANGE	96..136	CDD:128787	7/40 (18%)
her9	NP_571948.1	bHLH-O_HES1_4	33..95	CDD:381465	31/62 (50%)
		Hairy_orange	109..147	CDD:462193	7/37 (19%)