Protein Alignment E(spl)m3-HLH and her4.4

DIOPT Version :10

• Sequence 1: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: NP_001121862.1
• Gene: her4.4 / 100149066
• ZFINID: ZDB-GENE-081031-104
• Length: 152
• Species: Danio rerio
• Alignment Length: 220
• Identity: 56/220 - (25%)
• Similarity: 86/220 - (39%)
• Gaps: 82/220 - (37%)

  Fly     7 KTYQYRKVMKPLLERKRRARINKCLDDLKDLMV-ECLQQEGEHVTRLEKADILELTVDHMRKLKQ 70
            :|....|:.||::|:.||.|||..::.||.|:. |.::|:.:  :|.|||||||:|:|.:|:
Zfish    13 ETLLTNKLRKPMVEKIRRERINSSIEKLKTLLAQEFVKQQPD--SRQEKADILEMTLDFLRR--- 72

  Fly    71 RGGLSLQGVVAGVGSPPTSTSTAHVESFRSGYV-HAADQITQVLLQTQQTDEIGRKIMKFLSTRL 134
                |.:...||.|              ||..| .|...::|..:|||.            .|||
Zfish    73 ----SQKSSAAGDG--------------RSRCVQEAVSFLSQCPVQTQS------------HTRL 107

  Fly   135 IELQTQLLQQQQQQQQHQQQQIPQSSGRLAFPLLGGYGPAAAAAAISYSSFLTSKDELIDVTSVD 199
            ::|   .|..|....||.:...||::.:.|
Zfish   108 MKL---FLHMQTPADQHTRVDNPQTTEKHA----------------------------------- 134

  Fly   200 GNALSETASVSSQESGASEPVWRPW 224
                   .|.:.|.:.|...:||||
Zfish   135 -------NSSAKQHTPARSHIWRPW 152

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m3-HLH	NP_524509.2	bHLH-O_ESMB_like	5..71	CDD:381584	26/64 (41%)
		ORANGE	96..136	CDD:128787	11/40 (28%)
her4.4	NP_001121862.1	bHLH-O_HES5	19..77	CDD:381467	26/66 (39%)
		ORANGE	77..123	CDD:128787	19/74 (26%)