DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment E(spl)m3-HLH and hes6.1

DIOPT Version :9

Sequence 1:	NP_524509.2	Gene:	E(spl)m3-HLH / 43156	FlyBaseID:	FBgn0002609	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	XP_017949954.1	Gene:	hes6.1 / 100126814	XenbaseID:	XB-GENE-1018104	Length:	195	Species:	Xenopus tropicalis

Alignment Length:	227	Identity:	53/227 - (23%)
Similarity:	89/227 - (39%)	Gaps:	67/227 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 KPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRKLKQRGGLSLQGVV 80
            |||:|::||||||:.|.||:.::     .:.|..:::|.|::|||||..:.::       |:...
Frog    18 KPLVEKRRRARINESLQDLRGIL-----SDTEFQSKMENAEVLELTVKRVERI-------LRNRT 70

  Fly    81 AGVGSPPTSTSTAHVESFRSGYVHAADQITQVLLQTQQTDEIGRKIMKFLSTRLIELQTQLLQQQ 145
            |.........|    |.|.:||:....::...:......|              ..|..:||
Frog    71 AEADRLQREAS----ERFAAGYIQCMHEVHTFVSSCPGID--------------ASLAAELL--- 114

  Fly   146 QQQQQHQQQQIPQSSGRLAFPLLG----------GYGPAAAAAAISYSSFLTSKDELIDVTSVDG 200
                .|..:.:|.|.|.|...::.          |.|.....:        :|:|...|:...:|
Frog   115 ----NHLLESMPLSEGSLQDLVMDVLLDSTSSEEGCGLGVLGS--------SSEDSCSDMEESEG 167

  Fly   201 NALSETASVSS-QESGASEPV-------WRPW 224
                |.|.:.| |:||.:..:       ||||
Frog   168 ----EKAGMGSVQDSGRTPEIQPPTPTMWRPW 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m3-HLH	NP_524509.2	HLH	11..70	CDD:238036	21/53 (40%)
E(spl)m3-HLH	NP_524509.2	ORANGE	96..136	CDD:128787	5/39 (13%)
hes6.1	XP_017949954.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	88	1.000	Inparanoid score	I4979
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1483774at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.970