Protein Alignment E(spl)m3-HLH and hes5.3

DIOPT Version :9

• Sequence 1: NP_524509.2
• Gene: E(spl)m3-HLH / 43156
• FlyBaseID: FBgn0002609
• Length: 224
• Species: Drosophila melanogaster
• Sequence 2: XP_002933894.1
• Gene: hes5.3 / 100101782
• XenbaseID: XB-GENE-480450
• Length: 160
• Species: Xenopus tropicalis
• Alignment Length: 220
• Identity: 51/220 - (23%)
• Similarity: 82/220 - (37%)
• Gaps: 83/220 - (37%)

  Fly     8 TYQYRKVMKPLLERKRRARINKCLDDLKDLM---VECLQQEGEHVTRLEKADILELTVDHMRKLK 69
            |.|..|:.||::|:.||.|||..::.|::|:   .:.||.:    ::.||||||||.|   :.||
 Frog    21 TKQKNKIRKPMVEKMRRDRINSSINQLQNLLEKEFQLLQPD----SKPEKADILELAV---KFLK 78

  Fly    70 QRGGLSLQGVVAGVGSPPTSTSTAHVESFRSGYVHAADQITQVLLQTQQTDEIGRKIMKFLSTRL 134
            |:  :..|          :..:....:.|..||.:...: |...|...:|:|
 Frog    79 QQ--ICSQ----------SKNNRKDYQDFSQGYSNCLHE-TFAFLSFHRTEE------------- 117

  Fly   135 IELQTQLLQQQQQQQQHQQQQIPQSSGRLAFPLLGGYGPAAAAAAISYSSFLTSKDELIDVTSVD 199
             |:|.:|:...|.... |.:.|..||.....|     ||.|
 Frog   118 -EMQLKLMNHFQCLDS-QPRGISVSSSHQKGP-----GPVA------------------------ 151

  Fly   200 GNALSETASVSSQESGASEPVWRPW 224
                            :::.:||||
 Frog   152 ----------------STKILWRPW 160

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)m3-HLH	NP_524509.2	HLH	11..70	CDD:238036	23/61 (38%)
		ORANGE	96..136	CDD:128787	7/39 (18%)
hes5.3	XP_002933894.1	bHLH-O_HES5	26..84	CDD:381467	25/66 (38%)
		Hairy_orange	93..135	CDD:383064	12/57 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1011
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000