Protein Alignment E(spl)mbeta-HLH and HES7

DIOPT Version :9

• Sequence 1: NP_524505.2
• Gene: E(spl)mbeta-HLH / 43152
• FlyBaseID: FBgn0002733
• Length: 195
• Species: Drosophila melanogaster
• Sequence 2: XP_016880721.1
• Gene: HES7 / 84667
• HGNCID: 15977
• Length: 265
• Species: Homo sapiens
• Alignment Length: 235
• Identity: 62/235 - (26%)
• Similarity: 92/235 - (39%)
• Gaps: 73/235 - (31%)

  Fly    15 KVMKPMLERKRRARINKCLDELKDIMVECLTQEGEHITRLEKADILELTVEHMKKL--------- 70
            |::||::|::||.|||:.|:||:.:::|....:.....:||||:|||..|.::::.
Human    49 KMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLRERSRVEPPAAA 113

  Fly    71 -----RAQKQ-----------------LRLSSVTGGVSPSADPKLSIAESFRA--GYVHAANEVS 111
                 |:..|                 |||::.....||:|.     |:.|.|  ||:.......
Human   114 APGVPRSPVQDAEALASCYLSGFRECLLRLAAFAHDASPAAR-----AQLFSALHGYLRPKPPRP 173

  Fly   112 KTL---AAVPGVSVD-----LGTQLMS----HLGH---RLNYLQVVVPSL------PIGVPLQAP 155
            |.:   ...|..|:|     ||..|..    |.||   |..:    .|||      ..|.|  ||
Human   174 KPVDPRPPAPRPSLDPAAPALGPALHQRPPVHQGHPSPRCAW----SPSLCSPRAGDSGAP--AP 232

  Fly   156 VEDQAMVTPPPSECDSLESGACSPAPSEASSTSGPMWRPW 195
            :.......|||...|........|.|:        .||||
Human   233 LTGLLPPPPPPHRQDGAPKAPLPPPPA--------FWRPW 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mbeta-HLH	NP_524505.2	HLH	13..75	CDD:238036	22/73 (30%)
		ORANGE	97..141	CDD:128787	15/60 (25%)
HES7	XP_016880721.1	HLH	49..108	CDD:238036	21/58 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140948
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740