Protein Alignment E(spl)mbeta-HLH and Hes5

DIOPT Version :9

• Sequence 1: NP_524505.2
• Gene: E(spl)mbeta-HLH / 43152
• FlyBaseID: FBgn0002733
• Length: 195
• Species: Drosophila melanogaster
• Sequence 2: XP_038966759.1
• Gene: Hes5 / 79225
• RGDID: 621340
• Length: 196
• Species: Rattus norvegicus
• Alignment Length: 225
• Identity: 62/225 - (27%)
• Similarity: 100/225 - (44%)
• Gaps: 70/225 - (31%)

  Fly     5 MEMSKTYQYRKVMKPMLERKRRARINKCLDELKDIMVECLTQEGEHITRLEKADILELTVEHMK- 68
            :||....:..::.||::|:.||.|||..:::|| :::|......:..::||||||||:.|.::|
  Rat     8 VEMLSPKEKNRLRKPVVEKMRRDRINSSIEQLK-LLLEQEFARHQPNSKLEKADILEMAVSYLKH 71

  Fly    69 ---KLRAQKQLRLSSVTGGVSP-----------------SADPKLSIAESFRAGYVHAANEVSK- 112
               :|.|..::.|.:   ||:|                 :|.|| |:.:.:..||.....|..:
  Rat    72 SKGELGACARVLLPT---GVAPTARAPLMPLGLPTAFAAAAGPK-SLHQDYSEGYSWCLQEAVQF 132

  Fly   113 -TLAAVPGVSVDLGTQLMSHLGHRLNYLQVVVPSLPIGVPLQAPVEDQAMVTPPPSECDSLESGA 176
             ||.|    :.|...:|:.|...         |..|     .|||::    ||.|        ||
  Rat   133 LTLHA----ASDTQMKLLYHFQR---------PPAP-----AAPVKE----TPTP--------GA 167

  Fly   177 CSPAPSEAS-------STSGP----MWRPW 195
             :|.|:.:|       |||..    :||||
  Rat   168 -APQPARSSTKAAASVSTSRQSACGLWRPW 196

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mbeta-HLH	NP_524505.2	HLH	13..75	CDD:238036	23/65 (35%)
		ORANGE	97..141	CDD:128787	9/45 (20%)
Hes5	XP_038966759.1	bHLH-O_HES5	18..74	CDD:381467	21/56 (38%)
		ORANGE	116..158	CDD:128787	11/59 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334611
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1011
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840