Protein Alignment E(spl)mbeta-HLH and bhlhe40

DIOPT Version :10

• Sequence 1: NP_524505.2
• Gene: E(spl)mbeta-HLH / 43152
• FlyBaseID: FBgn0002733
• Length: 195
• Species: Drosophila melanogaster
• Sequence 2: XP_004914192.2
• Gene: bhlhe40 / 779502
• XenbaseID: XB-GENE-486416
• Length: 385
• Species: Xenopus tropicalis
• Alignment Length: 207
• Identity: 60/207 - (28%)
• Similarity: 96/207 - (46%)
• Gaps: 52/207 - (25%)

  Fly     7 MSKTYQYRKVMK--------------PMLERKRRARINKCLDELKDIMVE--CLTQEGEHITRLE 55
            |...:::||.:|              .::|:|||.|||:|:.:|||::.|  .||..|    .||
 Frog    54 MYPVFKHRKALKRCEESKQDTYKLPHRLIEKKRRDRINECIAQLKDLLPEHLKLTTLG----HLE 114

  Fly    56 KADILELTVEHMKKLRA---QKQLRLSSVTGGVSPSADPKLSIAESFRAGYVHAANEVSKTLAAV 117
            ||.:||||::|::.|.:   |:|.::.::..| |||.:.::|..|.|.:|:...|.|..:.|..
 Frog   115 KAVVLELTLKHVRSLSSLIEQQQQQILTLQSG-SPSEENRISAEEMFHSGFQLCAEEALRFLQG- 177

  Fly   118 PGVSVDLG--TQLMSHLGHRLNYLQVVVPSL-PIGVP--LQAPVEDQAMVTPPPSECDSLESGAC 177
                   |  .:|::|| ||      |...| |...|  .:.||        |..:..:.....|
 Frog   178 -------GERKELVAHL-HR------VASKLGPASFPKVTEKPV--------PKVQATNCVPVIC 220

  Fly   178 SPAPSEASSTSG 189
            ..||..:...||
 Frog   221 RAAPLPSGEQSG 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mbeta-HLH	NP_524505.2	bHLH-O_ESMB_like	7..75	CDD:381584	30/86 (35%)
		ORANGE	97..141	CDD:128787	12/45 (27%)
bhlhe40	XP_004914192.2	bHLH_SF	61..151	CDD:469605	34/94 (36%)
		Hairy_orange	159..192	CDD:462193	12/47 (26%)