Protein Alignment E(spl)mbeta-HLH and Hes3

DIOPT Version :10

• Sequence 1: NP_524505.2
• Gene: E(spl)mbeta-HLH / 43152
• FlyBaseID: FBgn0002733
• Length: 195
• Species: Drosophila melanogaster
• Sequence 2: NP_073178.1
• Gene: Hes3 / 64628
• RGDID: 621339
• Length: 175
• Species: Rattus norvegicus
• Alignment Length: 196
• Identity: 60/196 - (30%)
• Similarity: 83/196 - (42%)
• Gaps: 42/196 - (21%)

  Fly    21 LERKRRARINKCLDELKDIMVECLTQEGEHITR---LEKADILELTVEHMKKLRAQKQLRLSSVT 82
            :|:|||||||..|::|:.:    |.:...|..|   |||||||||:|::::.|:...| .|..|.
  Rat     1 MEKKRRARINLSLEQLRSL----LERHYSHQIRKRKLEKADILELSVKYVRSLQNSLQ-GLWLVP 60

  Fly    83 GGVS-PSADPKLSIAESFRAGYVHAANEVSKTLAAVPGVSVDLGTQLMSHLGHRL---------N 137
            .||. ||         .||.|...::..:.      ||.. |.|.:....|..|.         .
  Rat    61 SGVDYPS---------GFRGGLPGSSQRLR------PGED-DSGLRCPLLLQRRAGSTTDSANPQ 109

  Fly   138 YLQVVVPSLP-IGVPLQAPVEDQAMVTPPPSECDSLES--GACSPAPSEASSTSGP-----MWRP 194
            ...|:.|.|| |..|.......|:..:|.|.....|||  |..:|.|:.......|     :|||
  Rat   110 TASVLSPCLPAIWAPGPPAGGSQSPQSPFPPLGGLLESSTGILAPPPASNCQAENPRPGFRVWRP 174

  Fly   195 W 195
            |
  Rat   175 W 175

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mbeta-HLH	NP_524505.2	bHLH-O_ESMB_like	7..75	CDD:381584	24/56 (43%)
		ORANGE	97..141	CDD:128787	9/52 (17%)
Hes3	NP_073178.1	bHLH-O_HES3	1..55	CDD:381503	25/58 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..175		13/50 (26%)
		WRPW motif	172..175		2/2 (100%)