DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment E(spl)mbeta-HLH and Helt

DIOPT Version :9

Sequence 1:NP_524505.2 Gene:E(spl)mbeta-HLH / 43152 FlyBaseID:FBgn0002733 Length:195 Species:Drosophila melanogaster
Sequence 2:XP_008769494.1 Gene:Helt / 498633 RGDID:1564073 Length:241 Species:Rattus norvegicus


Alignment Length:234 Identity:55/234 - (23%)
Similarity:83/234 - (35%) Gaps:80/234 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 MSKTYQYRK---VMKPMLERKRRARINKCLDELKDIMVECLTQEGEHITRLEKADILELTVEHMK 68
            ||...:.||   |...::|::||.|||:||:||...:...|.::..  .:||||:|||:||::::
  Rat     1 MSDRLKERKRTPVSHKVIEKRRRDRINRCLNELGKTVPMALAKQSS--GKLEKAEILEMTVQYLR 63

  Fly    69 KLRAQKQLRLSSVTGGVSPSADPKLSIAESFRAGYVHAANEVSKTLAAVPGVSVDLGTQLMSHLG 133
            .|.:..           .|....|..:...| |.|.|....                 :.|.:|.
  Rat    64 ALHSAD-----------FPRGREKAELLAEF-ANYFHYGYH-----------------ECMKNLV 99

  Fly   134 HRL-----------NYLQVVV-----------PSLPIGVPLQAPVEDQAMVTPP---------PS 167
            |.|           .|.:::.           |:.|   ||..|..|.:....|         |.
  Rat   100 HYLTTVERMETKDTKYARILAFLQSKARLGAEPAFP---PLSLPEPDFSYQLHPAGPEFPGHSPG 161

  Fly   168 ECDSLESGAC------------SPAPSEASSTSGPMWRP 194
            |......||.            |||....||.:.|:..|
  Rat   162 EATVFPQGATPGSFPWPPGAARSPALPYLSSATVPLPTP 200

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
E(spl)mbeta-HLHNP_524505.2 HLH 13..75 CDD:238036 24/64 (38%)
ORANGE 97..141 CDD:128787 9/54 (17%)
HeltXP_008769494.1 bHLH-O_HELT 14..69 CDD:381414 21/56 (38%)
Hairy_orange 87..127 CDD:400076 6/56 (11%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166334539
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.840

Return to query results.
Submit another query.