Protein Alignment E(spl)mbeta-HLH and Helt

DIOPT Version :10

• Sequence 1: NP_524505.2
• Gene: E(spl)mbeta-HLH / 43152
• FlyBaseID: FBgn0002733
• Length: 195
• Species: Drosophila melanogaster
• Sequence 2: XP_008769494.1
• Gene: Helt / 498633
• RGDID: 1564073
• Length: 241
• Species: Rattus norvegicus
• Alignment Length: 234
• Identity: 55/234 - (23%)
• Similarity: 83/234 - (35%)
• Gaps: 80/234 - (34%)

  Fly     7 MSKTYQYRK---VMKPMLERKRRARINKCLDELKDIMVECLTQEGEHITRLEKADILELTVEHMK 68
            ||...:.||   |...::|::||.|||:||:||...:...|.::..  .:||||:|||:||::::
  Rat     1 MSDRLKERKRTPVSHKVIEKRRRDRINRCLNELGKTVPMALAKQSS--GKLEKAEILEMTVQYLR 63

  Fly    69 KLRAQKQLRLSSVTGGVSPSADPKLSIAESFRAGYVHAANEVSKTLAAVPGVSVDLGTQLMSHLG 133
            .|.:..           .|....|..:...| |.|.|....                 :.|.:|.
  Rat    64 ALHSAD-----------FPRGREKAELLAEF-ANYFHYGYH-----------------ECMKNLV 99

  Fly   134 HRL-----------NYLQVVV-----------PSLPIGVPLQAPVEDQAMVTPP---------PS 167
            |.|           .|.:::.           |:.|   ||..|..|.:....|         |.
  Rat   100 HYLTTVERMETKDTKYARILAFLQSKARLGAEPAFP---PLSLPEPDFSYQLHPAGPEFPGHSPG 161

  Fly   168 ECDSLESGAC------------SPAPSEASSTSGPMWRP 194
            |......||.            |||....||.:.|:..|
  Rat   162 EATVFPQGATPGSFPWPPGAARSPALPYLSSATVPLPTP 200

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mbeta-HLH	NP_524505.2	bHLH-O_ESMB_like	7..75	CDD:381584	26/70 (37%)
		ORANGE	97..141	CDD:128787	9/54 (17%)
Helt	XP_008769494.1	bHLH-O_HELT	14..69	CDD:381414	21/56 (38%)
		Hairy_orange	86..127	CDD:462193	7/57 (12%)
		DUF1373	129..>213	CDD:462093	18/75 (24%)