Protein Alignment E(spl)mbeta-HLH and her6

DIOPT Version :10

• Sequence 1: NP_524505.2
• Gene: E(spl)mbeta-HLH / 43152
• FlyBaseID: FBgn0002733
• Length: 195
• Species: Drosophila melanogaster
• Sequence 2: NP_571154.2
• Gene: her6 / 30288
• ZFINID: ZDB-GENE-980526-144
• Length: 270
• Species: Danio rerio
• Alignment Length: 254
• Identity: 69/254 - (27%)
• Similarity: 115/254 - (45%)
• Gaps: 86/254 - (33%)

  Fly    12 QYRKVMKPMLERKRRARINKCLDELKDIMVECLTQEGEHITRLEKADILELTVEHMKKL-RAQKQ 75
            ::||..||::|::||||||:.|.:||.::::.|.::....::||||||||:||:|::.: |||..
Zfish    33 EHRKSSKPIMEKRRRARINESLGQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNMQRAQMT 97

  Fly    76 LRLSSVTGGVSPSADPKLSIAESFRAGYVHAANEVSKTLAAVPGVSVDLGTQLMSHLG------H 134
            ..|::         ||  ::...:|||:....|||::.|:...||:.::.|:|:.||.      :
Zfish    98 AALNT---------DP--TVLGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHLASCMTQIN 151

  Fly   135 RLNYLQVVVPS---LPIGVP--------LQAP-VEDQAMVTP---PPSECDS------------- 171
            .:||     |:   :|.|.|        :|.| ...||.|.|   .|.:..|
Zfish   152 AMNY-----PTQHQIPAGPPHPSFSQPMVQIPSATQQANVVPLSGVPCKSGSSSNLTSDATKVYG 211

  Fly   172 ---------------LESGACSP--------------------APSEASSTSGPMWRPW 195
                           :.:.|.:|                    :|...|.||..:||||
Zfish   212 GFQLVPATDGQFAFLIPNAAFAPNGPVIPVYANNSNTPVPVAVSPGAPSVTSDSVWRPW 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mbeta-HLH	NP_524505.2	bHLH-O_ESMB_like	7..75	CDD:381584	29/63 (46%)
		ORANGE	97..141	CDD:128787	15/49 (31%)
her6	NP_571154.2	bHLH-O_HES1_4	33..95	CDD:381465	27/61 (44%)
		Hairy_orange	109..148	CDD:462193	13/38 (34%)