Protein Alignment E(spl)mbeta-HLH and her1

DIOPT Version :10

• Sequence 1: NP_524505.2
• Gene: E(spl)mbeta-HLH / 43152
• FlyBaseID: FBgn0002733
• Length: 195
• Species: Drosophila melanogaster
• Sequence 2: NP_571153.1
• Gene: her1 / 30287
• ZFINID: ZDB-GENE-980526-125
• Length: 328
• Species: Danio rerio
• Alignment Length: 330
• Identity: 69/330 - (20%)
• Similarity: 109/330 - (33%)
• Gaps: 146/330 - (44%)

  Fly     6 EMSKTYQYRKVMKPMLERKRRARINKCLDELKDIMVECLTQEGEHITRLEKADILELTVEHMKK- 69
            :|:.....::::||::|:|||.|||:.|:||:.::::..........:||||:||||.||:::.
Zfish     5 KMASRRPTKRILKPVIEKKRRDRINQRLEELRTLLLDNTLDSRLQNPKLEKAEILELAVEYIRTK 69

  Fly    70 ----------------------LRAQKQLRLSSVTGGV----SPS-------------------- 88
                                  |..:.|:..:|:...:    |||
Zfish    70 TATARDQGDSSKDTHDPKPPPLLSRRPQMPCASIPESIQTHNSPSNPIYKAGFKECISRSASFID 134

  Fly    89 -ADPKLSIAESFRAGYVHAANEVSKTLAA------------VPGVSVDLGTQLMSHLGH-RLN-- 137
             .:|  |..:||..|..|..:..|..|..            :|...:...|.:.| :|| |.|
Zfish   135 CVEP--SQRDSFVQGLCHHLDSYSSALPHGRVSSNPTHHPWIPNPELSCRTDVQS-IGHMRANPE 196

  Fly   138 ---YLQVVVPSL-----PIGVPLQAP-VEDQAMVTPPPSECDSLESGACSPAP------------ 181
               |...:.|..     |.|   |.| :.....::||||...|..|...|.:|
Zfish   197 PYSYANSLYPKSFMHLHPTG---QHPYLSPPYSISPPPSPGFSSSSPPFSSSPTYLSVPCQFPFP 258

  Fly   182 ---------SEASST-----------------------------SG------------------P 190
                     |.:|||                             ||                  |
Zfish   259 PSISPHSTDSSSSSTLSTVSLSTTSLPVVPGPHLQVSSPTRVRFSGSVQSSQPRTLRRALFHNQP 323

  Fly   191 MWRPW 195
            :||||
Zfish   324 LWRPW 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mbeta-HLH	NP_524505.2	bHLH-O_ESMB_like	7..75	CDD:381584	24/90 (27%)
		ORANGE	97..141	CDD:128787	14/61 (23%)
her1	NP_571153.1	bHLH_SF	13..73	CDD:469605	22/59 (37%)
		Hairy_orange	118..157	CDD:462193	6/40 (15%)