DRSC/TRiP Functional Genomics Resources

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Protein Alignment E(spl)mbeta-HLH and Helt

DIOPT Version :9

Sequence 1:NP_524505.2 Gene:E(spl)mbeta-HLH / 43152 FlyBaseID:FBgn0002733 Length:195 Species:Drosophila melanogaster
Sequence 2:XP_006509452.1 Gene:Helt / 234219 MGIID:3040955 Length:241 Species:Mus musculus


Alignment Length:234 Identity:56/234 - (23%)
Similarity:83/234 - (35%) Gaps:80/234 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 MSKTYQYRK---VMKPMLERKRRARINKCLDELKDIMVECLTQEGEHITRLEKADILELTVEHMK 68
            ||...:.||   |...::|::||.|||:||:||...:...|.::..  .:||||:|||:||::::
Mouse     1 MSDRLKERKRTPVSHKVIEKRRRDRINRCLNELGKTVPMALAKQSS--GKLEKAEILEMTVQYLR 63

  Fly    69 KLRAQKQLRLSSVTGGVSPSADPKLSIAESFRAGYVHAANEVSKTLAAVPGVSVDLGTQLMSHLG 133
            .|.:..           .|....|..:...| |.|.|....                 :.|.:|.
Mouse    64 ALHSAD-----------FPRGREKAELLAEF-ANYFHYGYH-----------------ECMKNLV 99

  Fly   134 HRL-----------NYLQVVV-----------PSLPIGVPLQAPVED---QAMVTPP------PS 167
            |.|           .|.:::.           |:.|   ||..|..|   |.....|      |.
Mouse   100 HYLTTVERMETKDTKYARILAFLQSKARLGAEPTFP---PLSLPEPDFSYQLHAASPEFPGHSPG 161

  Fly   168 ECDSLESGAC------------SPAPSEASSTSGPMWRP 194
            |......||.            |||....||.:.|:..|
Mouse   162 EATMFPQGATPGSFPWPPGAARSPALPYLSSATVPLPSP 200

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
E(spl)mbeta-HLHNP_524505.2 HLH 13..75 CDD:238036 24/64 (38%)
ORANGE 97..141 CDD:128787 9/54 (17%)
HeltXP_006509452.1 bHLH-O_HELT 14..69 CDD:381414 21/56 (38%)
Hairy_orange 87..127 CDD:369405 6/56 (11%)
PLN02983 <147..>213 CDD:215533 13/54 (24%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167830831
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4304
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.740

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