Protein Alignment E(spl)mbeta-HLH and Hes3

DIOPT Version :10

• Sequence 1: NP_524505.2
• Gene: E(spl)mbeta-HLH / 43152
• FlyBaseID: FBgn0002733
• Length: 195
• Species: Drosophila melanogaster
• Sequence 2: XP_011248491.1
• Gene: Hes3 / 15207
• MGIID: 104877
• Length: 291
• Species: Mus musculus
• Alignment Length: 200
• Identity: 62/200 - (31%)
• Similarity: 87/200 - (43%)
• Gaps: 40/200 - (20%)

  Fly    16 VMKPMLERKRRARINKCLDELKDIMVECLTQEGEHITR---LEKADILELTVEHMKKLRAQKQLR 77
            :.||::|:|||||||..|::|:.:    |.:...|..|   |||||||||:|::|:.|:...| .
Mouse   112 ISKPLMEKKRRARINVSLEQLRSL----LERHYSHQIRKRKLEKADILELSVKYMRSLQNSLQ-G 171

  Fly    78 LSSVTGGVSPSADPKLSIAESFRAGYVHAANEVSKTLAAVPGVSVDLGTQLMSHLGHR------- 135
            |..|..||            .:.:|:......||:.|.  ||.. |.|.:....|..|
Mouse   172 LWPVPSGV------------DYPSGFQGGLRGVSQRLR--PGEG-DSGLRCPLLLQRREGSTTDS 221

  Fly   136 --LNYLQVVVPSLP-IGVPLQAPVEDQAMVTPPPSECDSLESGACSPAPSEASSTSGP------- 190
              .....|:.|.|| |..|.:|.....:..:|.|.....|||.....||..||:....
Mouse   222 ANPQATSVLNPCLPAIWAPSRAAGGSHSPQSPLPLPGGLLESSTDVVAPHPASNCQAESTRPGFR 286

  Fly   191 MWRPW 195
            :||||
Mouse   287 VWRPW 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mbeta-HLH	NP_524505.2	bHLH-O_ESMB_like	7..75	CDD:381584	27/61 (44%)
		ORANGE	97..141	CDD:128787	10/52 (19%)
Hes3	XP_011248491.1	bHLH-O_HES3	117..171	CDD:381503	26/58 (45%)