Protein Alignment E(spl)mbeta-HLH and Hes2

DIOPT Version :10

• Sequence 1: NP_524505.2
• Gene: E(spl)mbeta-HLH / 43152
• FlyBaseID: FBgn0002733
• Length: 195
• Species: Drosophila melanogaster
• Sequence 2: NP_032262.2
• Gene: Hes2 / 15206
• MGIID: 1098624
• Length: 157
• Species: Mus musculus
• Alignment Length: 195
• Identity: 59/195 - (30%)
• Similarity: 85/195 - (43%)
• Gaps: 38/195 - (19%)

  Fly     1 MVLEMEMSKTYQYRKVMKPMLERKRRARINKCLDELKDIMVECLTQEGEHITRLEKADILELTVE 65
            |.|...:....:.||.:||:||::||||||:.|.:||.:::..|..|....::||||||||:||
Mouse     1 MRLPRRVEDAAELRKNLKPLLEKRRRARINESLSQLKGLVLPLLGAETSRSSKLEKADILEMTV- 64

  Fly    66 HMKKLRAQKQLRLSSVTGGVSPSADPKLSIAESFRAGYVHAANEVSKTLAAVPGVSVDLGTQLMS 130
              :.|:.|.....||...|      |..|..|.:||.....|..:.......|.||    .:|:.
Mouse    65 --RFLQEQPATLYSSAAPG------PLNSYLEGYRACLARLARVLPACSVLEPAVS----ARLLE 117

  Fly   131 HLGHRLNYLQVVVPSLPIGVPLQAPVEDQAMVTPPPSECDSLESGACSPAPSEASSTSGPMWRPW 195
            ||..|                  ...:|...:|.||:.       |.:|:|......|..:||||
Mouse   118 HLRQR------------------TVSDDSPSLTLPPAP-------APAPSPPVPPPGSSGLWRPW 157

  Fly   196  195
            Mouse   158  157

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mbeta-HLH	NP_524505.2	bHLH-O_ESMB_like	7..75	CDD:381584	29/67 (43%)
		ORANGE	97..141	CDD:128787	11/43 (26%)
Hes2	NP_032262.2	bHLH_SF	10..73	CDD:469605	29/65 (45%)
		ORANGE	85..123	CDD:128787	12/59 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..157		10/39 (26%)
		WRPW motif	154..157		2/2 (100%)