Protein Alignment E(spl)mbeta-HLH and hes3

DIOPT Version :10

• Sequence 1: NP_524505.2
• Gene: E(spl)mbeta-HLH / 43152
• FlyBaseID: FBgn0002733
• Length: 195
• Species: Drosophila melanogaster
• Sequence 2: XP_004916246.2
• Gene: hes3 / 100494165
• XenbaseID: XB-GENE-22064057
• Length: 208
• Species: Xenopus tropicalis
• Alignment Length: 226
• Identity: 60/226 - (26%)
• Similarity: 94/226 - (41%)
• Gaps: 66/226 - (29%)

  Fly     8 SKTYQYRKVMKPMLERKRRARINKCLDELKDIMVECLTQEGEHITRLEKADILELTVEHMKKLRA 72
            |.....|||.||::|:|||||||..|::||.::.:..:|.... .:|||||||||||:::|.|:
 Frog    11 SNPISLRKVSKPLMEKKRRARINVSLEQLKGLLEKNYSQNIRK-RKLEKADILELTVKYLKTLQ- 73

  Fly    73 QKQLRLSSVTGGVSPSADPKLSIAESFRAGYVHAANEVSKTLAAVPGVSVDLGTQLMSHLGHRLN 137
                  :|:..|     :| |..:..::||:.:..|.|::.|...            ...|...:
 Frog    74 ------NSIQAG-----NP-LYRSTEYQAGFRNCLNGVNQFLLRA------------DESGQAAH 114

  Fly   138 YLQVVVPSLPIGVPLQAPVEDQAMVTPP-----------------------------PSECD--- 170
            ..|.:..:||.........:|.|  :||                             ||:|.
 Frog   115 LTQDIARALPAVNTSYFSTKDSA--SPPANTTPYTQILAGKMGNSVTGTQTTKRRIAPSDCQLPT 177

  Fly   171 SLESGACS------PAPSEASSTSGPMWRPW 195
            ...||..:      .|||...:.:..:||||
 Frog   178 DRSSGHLAIQGHGLVAPSSNGAINQDVWRPW 208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mbeta-HLH	NP_524505.2	bHLH-O_ESMB_like	7..75	CDD:381584	31/66 (47%)
		ORANGE	97..141	CDD:128787	6/43 (14%)
hes3	XP_004916246.2	bHLH-O_HES3	24..77	CDD:381503	26/60 (43%)