Protein Alignment E(spl)mgamma-HLH and Hes7

DIOPT Version :9

• Sequence 1: NP_524504.2
• Gene: E(spl)mgamma-HLH / 43151
• FlyBaseID: FBgn0002735
• Length: 205
• Species: Drosophila melanogaster
• Sequence 2: NP_149030.2
• Gene: Hes7 / 84653
• MGIID: 2135679
• Length: 225
• Species: Mus musculus
• Alignment Length: 227
• Identity: 56/227 - (24%)
• Similarity: 96/227 - (42%)
• Gaps: 54/227 - (23%)

  Fly    17 KVMKPMLERKRRARINKCLDELKDLMVATLESEGEHVTRLEKADILELTVTHLQKMKQQRQH--K 79
            |::||::|::||.|||:.|:||:.|::.....:.....:||||:|||..|.:|::..:....  .
Mouse    14 KMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLRERSRVEPPGVP 78

  Fly    80 RASGDESLTPA----EGFR------SGYIHAVNEVSRSLSQLPGMNVSLGTQLMTHL-GQR---- 129
            |:.|.::...|    .|||      :.:.|..:..:||             ||.:.| |.|
Mouse    79 RSPGQDAEALASCYLSGFRECLLRLAAFAHDASPAARS-------------QLFSALHGYRRPKP 130

  Fly   130 -----LNQIQPAEKEVLPVTAPL---SVHIANRDAYSVPISP--------ISSYAGSPNSNTSST 178
                 ::...||.:..|...:|:   ::| .....:..|.||        .||.||  :|...:.
Mouse   131 PRPEAVDPGLPAPRPPLDPASPILGPALH-QRPPVHQGPPSPRLAWSPSHCSSRAG--DSGAPAP 192

  Fly   179 SHSLLTTIDVTKMEDDSEDEENV-----WRPW 205
            ...||........:|.:....::     ||||
Mouse   193 LTGLLPPPPPPYRQDGAPKAPSLPPPAFWRPW 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E(spl)mgamma-HLH	NP_524504.2	HLH	15..77	CDD:238036	22/59 (37%)
		ORANGE	91..135	CDD:128787	11/59 (19%)
Hes7	NP_149030.2	HLH	14..73	CDD:238036	22/58 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..225		22/104 (21%)
		WRPW motif	221..224		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830914
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4304
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740